In vitro cultured blood cells for transfusion purposes provide a safe alternative to donor
blood, particularly for patients who require recurrent transfusions, and can be used as …

Congenital coagulopathies have, throughout the history of medicine, been a focus of
scientific study and of great interest as they constitute an alteration of one of the most …

The prevailing hypotheses for the persistent symptoms of Long COVID have been narrowed
down to immune dysregulation and autoantibodies, widespread organ damage, viral …

The discovery of iPSCs has led to the ex vivo production of differentiated cells for
regenerative medicine. In the case of transfusion products, the derivation of platelets from …

Despite the recent advancements in transfusion medicine, red blood cell (RBC)
alloimmunization remains a challenge for multiparous women and chronically transfused …

Tamoxifen shows efficacy in reducing breast cancer-related mortality but clinically, is
associated with increased risk for thromboembolic events. We aimed to determine whether …

Background Thrombocytopenia leading to life‐threatening excessive bleeding can be
treated by platelet transfusion. Currently, such treatments are totally dependent on donor …

Human platelet membrane glycoprotein polymorphisms can be immunogenic in man and
are frequently the cause of clinically important immune reactions responsible for disorders …

Background Specifically positioned negatively charged residues within the cytoplasmic
domain of the adaptor protein, linker for the activation of T cells (LAT), have been shown to …

There is increasing awareness that platelets play a significant role in creating a
hypercoagulable environment that mediates tumor progression, beyond their classical …