[PDF][PDF] Hallmarks of health

C López-Otín, G Kroemer - Cell, 2021 - cell.com
Health is usually defined as the absence of pathology. Here, we endeavor to define health
as a compendium of organizational and dynamic features that maintain physiology. The …

[HTML][HTML] Sexual dimorphism in colon cancer

M Abancens, V Bustos, H Harvey, J McBryan… - Frontiers in …, 2020 - frontiersin.org
A higher incidence of colorectal cancer (CRC) is found in males compared to females.
Young women (18–44 years) with CRC have a better survival outcome compared to men of …

The gut-lung axis in cystic fibrosis

CE Price, GA O'Toole - Journal of bacteriology, 2021 - Am Soc Microbiol
Cystic fibrosis (CF) is a heritable, multiorgan disease that impacts all tissues that normally
express cystic fibrosis transmembrane conductance regulator (CFTR) protein. While the …

Intestinal inflammation and alterations in the gut microbiota in cystic fibrosis: a review of the current evidence, pathophysiology and future directions

RY Tam, JM van Dorst, I McKay, M Coffey… - Journal of Clinical …, 2022 - mdpi.com
Cystic fibrosis (CF) is a life-limiting autosomal recessive multisystem disease. While its
burden of morbidity and mortality is classically associated with pulmonary disease, CF also …

Impact of altered gut microbiota and its metabolites in cystic fibrosis

A Thavamani, I Salem, TJ Sferra, S Sankararaman - Metabolites, 2021 - mdpi.com
Cystic fibrosis (CF) is the most common lethal, multisystemic genetic disorder in Caucasians.
Mutations in the gene encoding the cystic fibrosis transmembrane regulator (CFTR) protein …

A cooperativity between virus and bacteria during respiratory infections

C Lalbiaktluangi, MK Yadav, PK Singh… - Frontiers in …, 2023 - frontiersin.org
Respiratory tract infections remain the leading cause of morbidity and mortality worldwide.
The burden is further increased by polymicrobial infection or viral and bacterial co-infection …

What do we know about the microbiome in cystic fibrosis? Is there a role for probiotics and prebiotics?

JM van Dorst, RY Tam, CY Ooi - Nutrients, 2022 - mdpi.com
Cystic fibrosis (CF) is a life-shortening genetic disorder that affects the cystic fibrosis
transmembrane conductance regulator (CFTR) protein. In the gastrointestinal (GI) tract …

Cancer in cystic fibrosis: a narrative review of prevalence, risk factors, screening, and treatment challenges: adult cystic fibrosis series

P Maisonneuve, AB Lowenfels - Chest, 2022 - Elsevier
Cystic fibrosis (CF) is a progressive monogenetic disorder that causes persistent pulmonary
disease, but also affects other organ systems, including the digestive tract. Recent advances …

Colorectal cancer: from risk factors to oncogenesis

VA Ionescu, G Gheorghe, N Bacalbasa, AL Chiotoroiu… - Medicina, 2023 - mdpi.com
Colorectal cancer is the second leading cause of cancer-related mortality worldwide.
Numerous pathophysiological mechanisms, such as abnormal cell proliferation, cell …

Early onset metastatic colorectal cancer: current insights and clinical management of a rising condition

B Medici, B Riccò, E Caffari, S Zaniboni, M Salati… - Cancers, 2023 - mdpi.com
Simple Summary In this review, the authors will discuss the highlights of early onset colon
cancer (EOCRC), an increasing but still unclear phenomenon. Indeed, the risk factors are …