Potential in exosome-based targeted nano-drugs and delivery vehicles for posterior ocular disease treatment: from barriers to therapeutic application

X Peng, T Zhang, R Liu, X Jin - Molecular and Cellular Biochemistry, 2023 - Springer
Posterior ocular disease, a disease that accounts for 55% of all ocular diseases, can
contribute to permanent vision loss if left without treatment. Due to the special structure of the …

Intractable ocular diseases and treatment progress

X Zhang, S Li, Y Tang, Y Guo, S Gao - AAPS PharmSciTech, 2020 - Springer
In recent years, with the aging of the population and the frequent use of electronic devices,
many eye diseases have shown a linear upward trend, such as dry eye disease, glaucoma …

A novel biomarker assay qualification strategy for rare human matrices–a case study of biomarkers in aqueous humor

JA Getz, T Nguy, R Dere, M Maia - Bioanalysis, 2024 - Taylor & Francis
Background: Measuring pharmacodynamic biomarkers near the therapeutic site of action
presents considerable challenges for sites with limited matrix volume or difficult access …

Ocular bioanalysis: challenges and advancements in recent years for these rare matrices

K Heinig, E Bertran, J Potter, D Fraier - Bioanalysis, 2017 - Future Science
There are many ocular diseases still presenting unmet medical needs. Therefore, new
ophthalmologic drugs are being developed. Bioanalysis of eye compartments (along with …

The classification of eye diseases from fundus images based on CNN and pretrained models

S Benbakreti, S Benbakreti, U Ozkaya - 2024 - dspace.cvut.cz
Visual impairment affects more than a billion people worldwide due to insufficient care or
inadequate vision screening. Computer-aided diagnosis using deep neural networks is a …