Sertoli cells are the orchestrators of spermatogenesis; they support fetal germ cell
commitment to the male pathway and are essential for germ cell development, from …

The elucidation of how individual components of the Sertoli cell junctional complexes form
and are dismantled to allow not only individual cells but whole syncytia of germinal cells to …

Tissue integrity relies on barriers formed between epithelial cells. In the testis, the barrier is
formed at the initiation of puberty by a tight junction complex between adjacent Sertoli cells …

Introduction: Sertoli cells support germ cell development in the testis via an elaborate
network of cell junctions that confers structural, communicating, and signaling support …

It has long been thought that mammalian Sertoli cells are terminally differentiated and
nondividing postpuberty. For most previous in vitro studies immature rodent testes have …

The blood-testis barrier (BTB) is known for its ability to create an immune privilege site in the
seminiferous epithelium, but less is known of the blood-epididymal barrier (BEB). It is …

New data have challenged the convention that the adult Sertoli cell population is fixed and
unmodifiable. The Sertoli cell has two distinct functions: 1) formation of the seminiferous …

Abstract STUDY QUESTION Can human Sertoli cells cultured in vitro and that have formed
an epithelium be used as a model to monitor toxicant-induced junction disruption and to …

The gastro-intestinal tract is an ecosystem containing trillions of commensal bacteria living in
symbiosis with the host. These microbiota modulate a variety of our physiological processes …

The endometrium becomes receptive to the embryo only in the mid-luteal phase, but not in
the other stages of the menstrual cycle. Endometrial factors play an important role in …