The vascular basement membrane in the healthy and pathological brain

MS Thomsen, LJ Routhe… - Journal of Cerebral Blood …, 2017 - journals.sagepub.com
The vascular basement membrane contributes to the integrity of the blood-brain barrier
(BBB), which is formed by brain capillary endothelial cells (BCECs). The BCECs receive …

Role and mechanisms of cytokines in the secondary brain injury after intracerebral hemorrhage

H Zhu, Z Wang, J Yu, X Yang, F He, Z Liu, F Che… - Progress in …, 2019 - Elsevier
Intracerebral hemorrhage (ICH) is a common and severe cerebrovascular disease that has
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …

Inflammation in intracerebral hemorrhage: from mechanisms to clinical translation

Y Zhou, Y Wang, J Wang, RA Stetler, QW Yang - Progress in neurobiology, 2014 - Elsevier
Intracerebral hemorrhage (ICH) accounts for 10–15% of all strokes and is associated with
high mortality and morbidity. Currently, no effective medical treatment is available to improve …

Immune interventions in stroke

Y Fu, Q Liu, J Anrather, FD Shi - Nature Reviews Neurology, 2015 - nature.com
Approaches for the effective management of acute stroke are sparse, and many measures
for brain protection fail. However, our ability to modulate the immune system and modify the …

Microglial responses after ischemic stroke and intracerebral hemorrhage

RA Taylor, LH Sansing - Journal of Immunology Research, 2013 - Wiley Online Library
Stroke is a leading cause of death worldwide. Ischemic stroke is caused by blockage of
blood vessels in the brain leading to tissue death, while intracerebral hemorrhage (ICH) …

Neuroinflammation after intracerebral hemorrhage

E Mracsko, R Veltkamp - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Spontaneous intracerebral hemorrhage (ICH) is a particularly severe type of stroke for which
no specific treatment has been established yet. Although preclinical models of ICH have …

Preclinical and clinical research on inflammation after intracerebral hemorrhage

J Wang - Progress in neurobiology, 2010 - Elsevier
Intracerebral hemorrhage (ICH) is one of the most lethal stroke subtypes. Despite the high
morbidity and mortality associated with ICH, its pathophysiology has not been investigated …

Mechanism and therapy of brain edema after intracerebral hemorrhage

H Zheng, C Chen, J Zhang, Z Hu - Cerebrovascular diseases, 2016 - karger.com
Background: Intracerebral hemorrhage (ICH) is a subtype of stroke with a severe high
mortality and disability rate and accounts for about 10-15% of all strokes. The oppression …

Microglia and macrophage phenotypes in intracerebral haemorrhage injury: therapeutic opportunities

Q Bai, M Xue, VW Yong - Brain, 2020 - academic.oup.com
The prognosis of intracerebral haemorrhage continues to be devastating despite much
research into this condition. A prominent feature of intracerebral haemorrhage is …

Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity

AD Kraft, GJ Harry - International journal of environmental research and …, 2011 - mdpi.com
Microglia are resident cells of the brain involved in regulatory processes critical for
development, maintenance of the neural environment, injury and repair. They belong to the …