Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): a review of clinical and MRI features, diagnosis, and management

E Sechi, L Cacciaguerra, JJ Chen, S Mariotto… - Frontiers in …, 2022 - frontiersin.org
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is the
most recently defined inflammatory demyelinating disease of the central nervous system …

Targeting B cells to modify MS, NMOSD, and MOGAD: part 1

J Graf, J Mares, M Barnett, O Aktas… - Neurology …, 2020 - AAN Enterprises
Ocrelizumab, rituximab, ofatumumab, ublituximab, inebilizumab, and evobrutinib are
immunotherapies that target various B cell–related proteins. Most of these treatments have …

Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD)–revised recommendations of the Neuromyelitis Optica Study Group …

T Kümpfel, K Giglhuber, O Aktas, I Ayzenberg… - Journal of …, 2024 - Springer
This manuscript presents practical recommendations for managing acute attacks and
implementing preventive immunotherapies for neuromyelitis optica spectrum disorders …

Rituximab in multiple sclerosis: are we ready for regulatory approval?

S Brancati, L Gozzo, L Longo, DC Vitale… - Frontiers in …, 2021 - frontiersin.org
Despite the availability of a lot of effective disease-modifying drugs, multiple sclerosis
(MS)(in particular the progressive forms) still represents an important unmet medical need …

Hypogammaglobulinemia and infections in patients with multiple sclerosis treated with rituximab

M Perriguey, A Maarouf, JP Stellmann… - Neurology …, 2021 - AAN Enterprises
Background and Objectives To determine the frequency of hypogammaglobulinemia and
infections in patients with multiple sclerosis (PwMS) receiving rituximab (RTX). Methods This …

Sustained low relapse rate with highly variable B-cell repopulation dynamics with extended rituximab dosing intervals in multiple sclerosis

C Starvaggi Cucuzza, E Longinetti… - Neurology …, 2022 - AAN Enterprises
Background and Objectives B cell–depleting therapies are highly effective in relapsing-
remitting multiple sclerosis (RRMS) but are associated with increased infection risk and …

Rituximab-induced hypogammaglobulinemia and risk of infection in neuromyelitis optica spectrum disorders: a 14-year real-life experience

SH Kim, NY Park, KH Kim, JW Hyun… - Neurology …, 2022 - AAN Enterprises
Background and Objectives To investigate the frequency and predictors of
hypogammaglobulinemia during long-term rituximab (RTX) treatment in patients with …

Advances in the treatment of neuromyelitis optica spectrum disorder

AI Wallach, M Tremblay, I Kister - Neurologic Clinics, 2021 - neurologic.theclinics.com
Neuromyelitis optica spectrum disorder (NMOSD) is a rare, relapsing-remitting
neuroinflammatory disorder of the central nervous system (CNS) usually associated with …

[HTML][HTML] Secondary hypogammaglobulinemia in patients with multiple sclerosis on anti-CD20 therapy: pathogenesis, risk of infection, and disease management

E Alvarez, EE Longbrake, KW Rammohan… - Multiple Sclerosis and …, 2023 - Elsevier
Hypogammaglobulinemia is characterized by reduced serum immunoglobulin levels.
Secondary hypogammaglobulinemia is of considerable interest to the practicing physician …

Multiple sclerosis, disease-modifying therapies, and infections

AM Langer-Gould, JB Smith, EG Gonzales… - Neurology …, 2023 - AAN Enterprises
Background and Objectives The use of highly effective multiple sclerosis (MS) disease-
modifying therapies (DMTs) is rapidly increasing. Yet, little is known about their real-world …