[HTML][HTML] Diet in the prevention of Alzheimer's disease: current knowledge and future research requirements

O Stefaniak, M Dobrzyńska, S Drzymała-Czyż… - Nutrients, 2022 - mdpi.com
Alzheimer's disease is a progressive brain disease that is becoming a major health problem
in today's world due to the aging population. Despite it being widely known that diet has a …

A straightforward access to trifluoromethylated natural products through late-stage functionalization

HP Li, XH He, C Peng, JL Li, B Han - Natural Product Reports, 2023 - pubs.rsc.org
Covering: 2011 to 2021 Trifluoromethyl (CF3)-modified natural products have attracted
increasing interest due to their magical effect in binding affinity and/or drug metabolism and …

[HTML][HTML] Propentofylline improves thiol-based antioxidant defenses and limits lipid peroxidation following gliotoxic injury in the rat brainstem

DEM Baliellas, MP Barros, CV Vardaris, M Guariroba… - Biomedicines, 2023 - mdpi.com
Propentofylline (PROP) is a methylated xanthine compound that diminishes the activation of
microglial cells and astrocytes, which are neuronal cells strongly associated with many …

[HTML][HTML] Caffeine synthesis and its mechanism and application by microbial degradation, a review

Z Lin, J Wei, Y Hu, D Pi, M Jiang, T Lang - Foods, 2023 - mdpi.com
Caffeine is a metabolite derived from purine nucleotides, typically accounting for 2–5% of
the dry weight of tea and 1–2% of the dry weight of coffee. In the tea and coffee plants, the …

Pentoxifylline Enhances Antioxidative Capability and Promotes Mitochondrial Biogenesis in D‐Galactose‐Induced Aging Mice by Increasing Nrf2 and PGC‐1α …

Y Wang, T Zhang, H Zhao, C Qi, X Ji… - Oxidative Medicine …, 2021 - Wiley Online Library
Aging is a complex phenomenon associated with oxidative stress and mitochondrial
dysfunction. The objective of this study was to investigate the potential ameliorative effects of …

[HTML][HTML] Biological Potential and Mechanisms of Tea's Bioactive Compounds in Tea: An Updated Review

Q Luo, L Luo, J Zhao, Y Wang, H Luo - Journal of Advanced Research, 2023 - Elsevier
Abstract Background Tea (Camellia sinensis) has a rich history and is widely consumed
across many countries, and is categorized into green tea, white tea, oolong tea, yellow tea …

Microbial metabolism of caffeine and potential applications in bioremediation

MB Mock, RM Summers - Journal of Applied Microbiology, 2024 - academic.oup.com
With increasing global consumption of caffeine-rich products, such as coffee, tea, and
energy drinks, there is also an increase in urban and processing waste full of residual …

[HTML][HTML] Eating habits and disease risk factors

KE Przybyłowicz, A Danielewicz - Nutrients, 2022 - mdpi.com
Diet plays an inevitable role in human health and disease prevention. However, personal
dietary choices involve not only what food and nutrients are consumed but also why, how …

Modulation of adenosine signaling reverses 3-nitropropionic acid-induced bradykinesia and memory impairment in adult zebrafish

MT Wiprich, S Altenhofen, D Gusso… - Progress in Neuro …, 2022 - Elsevier
Huntington's disease (HD) is a neurodegenerative disorder, characterized by motor
dysfunction, psychiatric disturbance, and cognitive decline. In the early stage of HD, occurs a …

Biocatalytic production and purification of the high-value biochemical paraxanthine

MB Mock, SB Mills, A Cyrus, H Campo… - Biotechnology and …, 2022 - Springer
Abstract Paraxanthine (1, 7-dimethylxanthine), a purine alkaloid derivative of caffeine (1, 3, 7-
trimethylxanthine), is a high-value biochemical with several applications in the …