Although osteoarthritis (OA) aetiology is complex, genetic, genomic and epigenetic studies
published within the last decade have advanced our understanding of the molecular …

Articular cartilage lesion such as osteoarthritis (OA) is becoming a serious threat to global
human health. In recent years, as a new paradigm in cartilage tissue engineering and …

MicroRNAs have been shown to function in cartilage development and homeostasis, as well
as in progression of osteoarthritis. The objective of the current study was to identify …

The purpose of this narrative review is to provide an overview of last year's publications in
the field of genetics, genomics and epigenetics in the osteoarthritis (OA) field. Major themes …

Osteoarthritis (OA) is progressive disease characterised by cartilage degradation,
subchondral bone remodelling and inflammation of the synovium. The disease is associated …

MicroRNAs (miRNAs) have a critical role in tumorigenesis and metastasis, which are major
obstacles of cancer therapy. However, the role of miRNAs in colorectal cancer (CRC) …

Osteoarthritis (OA) is the most common type of arthritis and no longer is considered as an
absolute consequence of joint mechanical use (wear and tear); rather recent data …

Osteoarthritis (OA) is a common and troublesome disease among the elderly, and is
characterized by extracellular matrix (ECM) degradation. The function of the long non …

MicroRNAs (miRNAs) are small non-coding RNAs that posttranscriptionally regulate the
expression of most genes. They are involved in regulating many physiological processes …

Abstract The Hedgehog (Hh) signalling pathway plays important roles during embryonic
development and in adult tissue homeostasis, for example cartilage, where its deregulation …