Antibiotic use and misuse in the neonatal intensive care unit

N Tripathi, CM Cotten, PB Smith - Clinics in …, 2012 - perinatology.theclinics.com
Antibiotics are the most commonly used therapeutics in neonatal intensive care units
(NICUs). 1 Neonatal sepsis often has a subtle, nonspecific presentation and results in …

Group B streptococcal disease in infants: progress in prevention and continued challenges

JR Verani, SJ Schrag - Clinics in perinatology, 2010 - perinatology.theclinics.com
The burden of early onset neonatal sepsis due to group B Streptococcus (GBS) has declined
substantially over the past 20 years as a result of widespread use of intrapartum antibiotic …

Interaction of Streptococcus agalactiae and Cellular Innate Immunity in Colonization and Disease

S Landwehr-Kenzel, P Henneke - Frontiers in immunology, 2014 - frontiersin.org
Streptococcus agalactiae (Group B streptococcus, GBS) is highly adapted to humans, where
it is a normal constituent of the intestinal and vaginal flora. Yet, GBS has highly invasive …

Effectiveness of intrapartum antibiotic prophylaxis for prevention of early-onset group B streptococcal disease

T Fairlie, ER Zell, S Schrag - Obstetrics & Gynecology, 2013 - journals.lww.com
OBJECTIVE: To estimate the effectiveness against early-onset group B streptococcal (GBS)
disease of intrapartum antibiotic prophylaxis among term and preterm deliveries, deliveries …

Capsular Switching in Group B Streptococcus CC17 Hypervirulent Clone: A Future Challenge for Polysaccharide Vaccine Development

S Bellais, A Six, A Fouet, M Longo… - The Journal of …, 2012 - academic.oup.com
Background. The capsular polysaccharide (CPS) is an important virulence factor and a
vaccine target of the major neonatal pathogen group B Streptococcus (GBS). Population …

The role of β-hemolytic streptococci in causing diffuse, nonculturable cellulitis: a prospective investigation

A Jeng, M Beheshti, J Li, R Nathan - Medicine, 2010 - journals.lww.com
Staphylococcus aureus and β-hemolytic streptococci (BHS) are the 2 main types of bacteria
causing soft-tissue infections. Historically, BHS were believed to be the primary cause of …

Streptococcus agalactiae in Brazil: serotype distribution, virulence determinants and antimicrobial susceptibility

VG Dutra, VMN Alves, AN Olendzki, CAG Dias… - BMC infectious …, 2014 - Springer
Abstract Background Group B Streptococcus (GBS) remains a major cause of neonatal
sepsis and is also associated with invasive and noninvasive infections in pregnant women …

[HTML][HTML] Group B Streptococcus neonatal invasive infections, France 2007–2012

C Joubrel, A Tazi, A Six, N Dmytruk, G Touak… - Clinical Microbiology …, 2015 - Elsevier
Streptococcus agalactiae (group B streptococcus (GBS)) is the leading cause of invasive
infections among newborns in industrialized countries, with two described syndromes: early …

Incidence and Severity of Invasive Streptococcus pneumoniae, Group A Streptococcus, and Group BStreptococcus Infections Among Pregnant and Postpartum …

M Deutscher, M Lewis, ER Zell… - Clinical infectious …, 2011 - academic.oup.com
Background. The epidemiology of streptococcal infection in pregnant and postpartum
women is poorly described in recent literature. We used data from multistate surveillance for …

Group B Streptococcus β-hemolysin/Cytolysin Breaches Maternal-Fetal Barriers to Cause Preterm Birth and Intrauterine Fetal Demise in Vivo

TM Randis, SE Gelber, TA Hooven… - The Journal of …, 2014 - academic.oup.com
Background. Maternal vaginal colonization with Streptococcus agalactiae (Group B
Streptococcus [GBS]) is a precursor to chorioamnionitis, fetal infection, and neonatal sepsis …