Role of oxidative stress in ocular diseases: a balancing act

DY Shu, S Chaudhary, KS Cho, A Lennikov, WP Miller… - Metabolites, 2023 - mdpi.com
Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …

Pathophysiology of age-related macular degeneration: implications for treatment

J Garcia-Garcia, R Usategui-Martin, MR Sanabria… - Ophthalmic …, 2022 - karger.com
Age-related macular degeneration (AMD) is a complex, multifactorial, progressive retinal
disease that affects millions of people worldwide and has become the leading cause of …

The potential for mitochondrial therapeutics in the treatment of primary open-angle glaucoma: a review

G Kuang, M Halimitabrizi, AA Edziah, R Salowe… - Frontiers in …, 2023 - frontiersin.org
Glaucoma, an age-related neurodegenerative disease, is characterized by the death of
retinal ganglion cells (RGCs) and the corresponding loss of visual fields. This disease is the …

Inhibition of acetylcholinesterase and amyloid-β aggregation by piceatannol and analogs: Assessing in vitro and in vivo impact on a murine model of scopolamine …

YY Sie, LC Chen, CJ Li, YH Yuan, SH Hsiao, MH Lee… - Antioxidants, 2023 - mdpi.com
Currently, no drug is effective in delaying the cognitive impairment of Alzheimer's disease,
which ranks as one of the top 10 causes of death worldwide. Hydroxylated stilbenes are …

A Narrative Review: The Effect and Importance of Carotenoids on Aging and Aging-Related Diseases

ER Bakac, E Percin, A Gunes-Bayir… - International Journal of …, 2023 - mdpi.com
Aging is generally defined as a time-dependent functional decline that affects most living
organisms. The positive increase in life expectancy has brought along aging-related …

Antioxidant Nutraceutical Strategies in the Prevention of Oxidative Stress Related Eye Diseases

U Rodella, C Honisch, C Gatto, P Ruzza… - Nutrients, 2023 - mdpi.com
This review aims to discuss the delicate balance between the physiological production of
reactive oxygen species and the role of antioxidant nutraceutical molecules in managing …

[HTML][HTML] Combined drug triads for synergic neuroprotection in retinal degeneration

V Maneu, P Lax, AMG De Diego, N Cuenca… - Biomedicine & …, 2022 - Elsevier
This review focuses on retina degeneration occurring during glaucoma, age-related macular
degeneration (AMD), diabetic retinopathy (DR), and retinitis pigmentosa (RP), and on the …

Association of vitamins with hearing loss, vision disorder and sleep problem in the US general population

Z Chen, L Yu, W Li, H Zhang, X Huang, W Chen… - … Science and Pollution …, 2023 - Springer
Based on nationally representative samples from US, we aimed to assess the associations
of vitamins with hearing loss, vision disorder and sleep problem. A total of 25,312, 8425 and …

Nutritional factors: benefits in glaucoma and ophthalmologic pathologies

M Musa, M Zeppieri, GN Atuanya, ES Enaholo… - Life, 2023 - mdpi.com
Glaucoma is a chronic optic neuropathy that can lead to irreversible functional and
morphological damage if left untreated. The gold standard therapeutic approaches in …

The role of citicoline and coenzyme Q10 in retinal pathology

C García-López, V García-López… - International Journal of …, 2023 - mdpi.com
Ocular neurodegenerative diseases such as glaucoma, diabetic retinopathy, and age-
related macular degeneration are common retinal diseases responsible for most of the …