Microfluidic devices enable novel means of emulating neurodegenerative disease
pathophysiology in vitro. These organ‐on‐a‐chip systems can potentially reduce animal …

Numerous studies to date have contributed to a paradigm shift in modeling cancer, moving
from the traditional two-dimensional culture system to three-dimensional (3D) culture …

Mesenchymal stem cells have contributed to the continuous progress of tissue engineering
and regenerative medicine. Adipose‐derived stem cells (ADSC) possess many advantages …

The heart is one of the most vital organs in the human body, which actively pumps the blood
through the vascular network to supply nutrients to as well as to extract wastes from all other …

Regenerative medicine and tissue engineering strategies have made remarkable progress
in remodeling, replacing, and regenerating damaged cardiovascular tissues. The design of …

Although brain metastases are common in cancer patients, little is known about the
mechanisms of cancer extravasation across the blood-brain barrier (BBB), a key step in the …

Vascularization, the formation of new blood vessels, is an essential biological process. As
the vasculature is involved in various fundamental physiological phenomena and closely …

Tissue barriers play a crucial role in human physiology by establishing tissue
compartmentalization and regulating organ homeostasis. At the interface between the …

This protocol describes how to form a 3D cell culture with explicit, endothelialized
microvessels. The approach leads to fully enclosed, perfusable vessels in a bioremodelable …

Cell migration has been recognized as one hallmark of malignant tumor progression. By
integrating the method of electrical cell–substrate impedance sensing (ECIS) with the …