Mitochondria and plasma membrane dual-targeted chimeric peptide for single-agent synergistic photodynamic therapy

H Cheng, RR Zheng, GL Fan, JH Fan, LP Zhao… - Biomaterials, 2019 - Elsevier
Mitochondria and cell membrane play important roles in maintaining cellular activity and
stability. Here, a single-agent self-delivery chimeric peptide based nanoparticle (designated …

Protein-based nanomaterials and nanosystems for biomedical applications: A review

S Ding, N Zhang, Z Lyu, W Zhu, YC Chang, X Hu, D Du… - Materials Today, 2021 - Elsevier
Advanced protein-based nanomaterials and nanosystems (PNNS) have attracted
considerable scientific interest in recent decades due to their potential in bio-applications …

Orthogonally engineered albumin with attenuated macrophage phagocytosis for the targeted visualization and phototherapy of liver cancer

WT Dou, P Qiu, Y Shi, L Zhu, C Guo, N Li… - Journal of the …, 2023 - ACS Publications
The five-year survival rate of hepatocellular carcinoma (HCC) remains unsatisfactory. This
reflects, in part, the paucity of effective methods that allow the target-specific diagnosis and …

Schiff base mediated dipeptide assembly toward nanoarchitectonics

Y Jia, X Yan, J Li - Angewandte Chemie International Edition, 2022 - Wiley Online Library
Dynamic covalent chemistry (DCC) is fascinating because of its dual nature. It perfectly
combines the reversible nature of noncovalent bonds with the robustness of covalent bonds …

Self-assembled injectable peptide hydrogels capable of triggering antitumor immune response

R Xing, S Li, N Zhang, G Shen, H Mohwald… - …, 2017 - ACS Publications
Self-assembled peptide hydrogels are particularly appealing for drug delivery, tissue
engineering, and antitumor therapy due to various advantageous features including …

A NIR-I light-responsive superoxide radical generator with cancer cell membrane targeting ability for enhanced imaging-guided photodynamic therapy

Y Bu, T Xu, X Zhu, J Zhang, L Wang, Z Yu, J Yu… - Chemical …, 2020 - pubs.rsc.org
Photodynamic therapy (PDT), as an emerging treatment modality, which takes advantage of
reactive oxygen species (ROS) generated upon light illumination to ablate tumours, has …

Tumor microenvironment-oriented adaptive nanodrugs based on peptide self-assembly

S Li, W Zhang, H Xue, R Xing, X Yan - Chemical Science, 2020 - pubs.rsc.org
The aberrant metabolism of tumor cells creates an inimitable microenvironment featuring
acidic pH, high glutathione (GSH) levels, and overexpression of certain enzymes, which …

[HTML][HTML] Stimuli-responsive peptide assemblies: Design, self-assembly, modulation, and biomedical applications

R Mu, D Zhu, S Abdulmalik, S Wijekoon, G Wei… - Bioactive materials, 2024 - Elsevier
Peptide molecules have design flexibility, self-assembly ability, high biocompatibility, good
biodegradability, and easy functionalization, which promote their applications as versatile …

Exploiting single atom iron centers in a porphyrin-like MOF for efficient cancer phototherapy

L Wang, X Qu, Y Zhao, Y Weng… - … applied materials & …, 2019 - ACS Publications
In recent years, single-atom catalysts (SACs) have attracted enormous attention due their
effectiveness in promoting a variety of catalytic reactions. However, the ability of SACs to …

Current limitations and recent progress in nanomedicine for clinically available photodynamic therapy

J Park, YK Lee, IK Park, SR Hwang - Biomedicines, 2021 - mdpi.com
Photodynamic therapy (PDT) using oxygen, light, and photosensitizers has been receiving
great attention, because it has potential for making up for the weakness of the existing …