Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic …

P Kamarajan, I Ateia, JM Shin, JC Fenno, C Le… - PLoS …, 2020 - journals.plos.org
Epidemiological studies reveal significant associations between periodontitis and oral
cancer. However, knowledge about the contribution of periodontal pathogens to oral cancer …

Importance of the immune system in head and neck cancer

AH Mirza, G Thomas, CH Ottensmeier, EV King - Head & Neck, 2019 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) are a heterogeneous group of tumors,
mainly caused by exposure to cigarette smoke and/or alcohol. In recent years, a virally …

Isolation and analysis of tumor‑derived extracellular vesicles from head and neck squamous cell carcinoma plasma by galectin‑based glycan recognition particles

L Benecke, DM Chiang… - International …, 2022 - spandidos-publications.com
Extracellular vesicles (EVs) have recently come into the spotlight as potential cancer
biomarkers. Isolation of pure EVs is complex, so wider use requires reliable and time …

Oncogenic role of ZFAS1 lncRNA in head and neck squamous cell carcinomas

T Kolenda, K Guglas, M Kopczyńska, A Teresiak… - Cells, 2019 - mdpi.com
Background: Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous
disease with high mortality. The identification of specific HNSCC biomarkers will increase …

Organotypic co-cultures as a novel 3D model for head and neck squamous cell carcinoma

L Engelmann, J Thierauf, N Koerich Laureano… - Cancers, 2020 - mdpi.com
Background: Head and neck squamous cell carcinomas (HNSCC) are phenotypically and
molecularly heterogeneous and frequently develop therapy resistance. Reliable patient …

[HTML][HTML] Expression of sex hormones in oral squamous cell carcinoma: a systematic review on immunohistochemical studies

R Saranya, R Chandini, K Mohideen, PN Adtani… - Cureus, 2022 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma (OSCC) is the most widespread oral malignancy. In the
western world, smoking and alcohol remain the most common risk factors, whereas …

The effect of NNK, a tobacco smoke carcinogen, on the miRNA and mismatch DNA repair expression profiles in lung and head and neck squamous cancer cells

SG Doukas, DP Vageli, G Lazopoulos, DA Spandidos… - Cells, 2020 - mdpi.com
Tobacco smoking is a common risk factor for lung cancer and head and neck cancer.
Molecular changes such as deregulation of miRNA expression have been linked to tobacco …

Tumor suppressor miRNA-503 inhibits cell invasion in head and neck cancer through the wnt signaling pathway via the WNT3A/MMP molecular axis

SJ Tang, KH Fan, GR You, SF Huang, CJ Kang… - International Journal of …, 2022 - mdpi.com
Head and neck cancer (HNC) is the fifth most common cancer worldwide, and its incidence
and death rates have been consistently high throughout the past decades. MicroRNAs …

Imaging-genomic study of head and neck squamous cell carcinoma: associations between radiomic phenotypes and genomic mechanisms via integration of the …

Y Zhu, ASR Mohamed, SY Lai, S Yang… - JCO clinical cancer …, 2019 - ascopubs.org
Purpose Recent data suggest that imaging radiomic features of a tumor could be indicative
of important genomic biomarkers. Understanding the relationship between radiomic and …

Saliva as a first-line diagnostic tool: A spectral challenge for identification of cancer biomarkers

C Paluszkiewicz, E Pięta, M Woźniak, N Piergies… - Journal of Molecular …, 2020 - Elsevier
The paper concentrates on the role of saliva in the early diagnosis of salivary gland tumor.
Due to the still not fully understood etiology of head and neck cancer, the fundamental …