In the central nervous system (CNS) of most vertebrates, oligodendrocytes enwrap neuronal
axons with extensions of their plasma membrane to form the myelin sheath. Several proteins …

The classic myelin basic protein (MBP) splice isoforms range in nominal molecular mass
from 14 to 21.5 kDa, and arise from the gene in the oligodendrocyte lineage (Golli) in …

An inducible program of inflammatory gene expression is central to antimicrobial defenses.
This response is controlled by a collaboration involving signal-dependent activation of …

In the central nervous system, a multilayered membrane layer known as the myelin sheath
enwraps axons, and is required for optimal saltatory signal conductance. The sheath …

Actin participates in several essential processes in the cell nucleus. Even though the
presence of actin in the nucleus was proposed more than 30 years ago, nuclear processes …

Nuclear export of messenger RNA (mRNA) through the nuclear pore complex (NPC) is an
indispensable step to ensure protein translation in the cytoplasm of eukaryotic cells. mRNA …

RNA–protein interactions are essential for proper gene expression regulation, particularly in
neurons with unique spatial constraints. Currently, these interactions are defined …

Spatiotemporal control of gene expression is important for neural development and function.
Here, we show that heterogeneous nuclear ribonucleoprotein (hnRNP) A/B is highly …

Myelination in the central nervous system provides a unique example of how cells establish
asymmetry. The myelinating cell, the oligodendrocyte, extends processes to and wraps …

Neurosteroids are defined as steroids de novo synthesized in the central nervous system.
While the production of neurosteroids is well documented in mammals and amphibians …