Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a superfamily of RNA-binding
proteins consisting of more than 20 members. These proteins play a crucial role in various …

In neurons certain mRNA transcripts are transported to synapses through mechanisms that
are not fully understood. Here we report that the heterogeneous nuclear ribonucleoprotein …

Background Accumulation of β-amyloid peptides is an important hallmark of Alzheimer's
disease (AD). Tremendous efforts have been directed to elucidate the mechanisms of β …

During spermatogenesis, mRNA localization and translation are believed to be regulated in
a stage-specific manner. We report here that the Protamine2 (Prm2) mRNA transits through …

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are two
incurable neurodegenerative disorders, often considered as the extreme manifestations of a …

Introduction Demyelination is one of the hallmarks of multiple sclerosis (MS). While
remyelination occurs during the disease, it is incomplete from the start and strongly …

In the central nervous system, oligodendroglial expression of myelin basic protein (MBP) is
crucial for the assembly and structure of the myelin sheath. MBP synthesis is tightly …

Recent years have witnessed a new turn in the field of gene expression regulation. Actin
and an ever‐growing family of actin‐associated proteins have been accepted as members …

In eukaryotic cells, gene expression is highly regulated at many layers. Nascent RNA
molecules are assembled into ribonucleoprotein complexes that are then released into the …

Copper is essential to mammalian physiology, and its homeostasis is tightly regulated. In
humans, genetic defects in copper excretion result in copper overload and Wilson's disease …