The intestinal milieu harbours the gut microbiota, consisting of a complex community of
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …

Previous studies have described that tumor organoids can capture the diversity of defined
human carcinoma types. Here, we describe conditions for long-term culture of human …

Skin cancer affects the lives of millions of people every year, as it is considered the most
popular form of cancer. In the USA alone, approximately three and a half million people are …

Testicular cancer is the most common malignancy among men between 14 and 44 years of
age, and its incidence has risen over the past two decades in Western countries. Both …

Background Despite recent improvements in prevention, diagnosis and treatment, vast
differences in melanoma burden still exist between populations. Comparative data can …

Curcumin diffuses through cell membranes into the endoplasmic reticulum, mitochondria,
and nucleus, where it exerts actions, as an antioxidant property. Therefore, its use has been …

The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …

Cancer is a fatal malignancy with high clinical significance and remains one of the major
causes of illness and death. It has no suitable cure existing till now. The safety and stability …

Small-cell lung cancer (SCLC) is an aggressive malignancy associated with a poor
prognosis. First-line treatment has remained unchanged for decades, and a paucity of …

The traditional approach to the treatment of patients with advanced-stage non-small-cell
lung carcinoma (NSCLC) harbouring ALK rearrangements or EGFR mutations has been the …