The mutual interplay of gut microbiota, diet and human disease
The intestinal milieu harbours the gut microbiota, consisting of a complex community of
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …
[HTML][HTML] The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017
Background Stomach cancer is a major health problem in many countries. Understanding
the current burden of stomach cancer and the differential trends across various locations is …
the current burden of stomach cancer and the differential trends across various locations is …
Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis
AC Ford, Y Yuan, P Moayyedi - Gut, 2020 - gut.bmj.com
Objectives Gastric cancer is strongly associated with Helicobacter pylori (H. pylori). We
conducted a previous systematic review and meta-analysis that suggested eradication …
conducted a previous systematic review and meta-analysis that suggested eradication …
Sustainable care for children with cancer: a Lancet Oncology Commission
We estimate that there will be 13· 7 million new cases of childhood cancer globally between
2020 and 2050. At current levels of health system performance (including access and …
2020 and 2050. At current levels of health system performance (including access and …
[HTML][HTML] Melatonin in cancer treatment: current knowledge and future opportunities
Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and
experimental studies have documented that melatonin could inhibit different types of cancer …
experimental studies have documented that melatonin could inhibit different types of cancer …
[HTML][HTML] Current status and future prospects for esophageal cancer
Simple Summary Over 500,000 individuals died due to esophageal cancer (EC) worldwide
in 2020. More than four decades of etiological research have predominantly focused on the …
in 2020. More than four decades of etiological research have predominantly focused on the …
[HTML][HTML] LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
J Tang, T Yan, Y Bao, C Shen, C Yu, X Zhu… - Nature …, 2019 - nature.com
Long non-coding RNAs (lncRNAs) contribute to colorectal cancer (CRC). However, the role
of lncRNAs in CRC metabolism, especially glucose metabolism remains largely unknown. In …
of lncRNAs in CRC metabolism, especially glucose metabolism remains largely unknown. In …
Healthcare and socioeconomic costs of NAFLD: A global framework to navigate the uncertainties
Left unaddressed, non-alcoholic fatty liver disease (NAFLD) will continue to have substantial
health, economic and social implications. To address the challenge, a paradigm shift is …
health, economic and social implications. To address the challenge, a paradigm shift is …
[HTML][HTML] Amplification of spatially isolated adenosine pathway by tumor–macrophage interaction induces anti-PD1 resistance in hepatocellular carcinoma
JC Lu, PF Zhang, XY Huang, XJ Guo, C Gao… - Journal of Hematology & …, 2021 - Springer
Background Immune checkpoint blockade resistance narrows the efficacy of cancer
immunotherapies, but the underlying mechanism remains elusive. Delineating the inherent …
immunotherapies, but the underlying mechanism remains elusive. Delineating the inherent …
Investigating novel resistance mechanisms to third-generation EGFR tyrosine kinase inhibitor osimertinib in non–small cell lung cancer patients
Z Yang, N Yang, Q Ou, Y Xiang, T Jiang, X Wu… - Clinical Cancer …, 2018 - AACR
Purpose: The third-generation EGFR tyrosine kinase inhibitor osimertinib is approved to
treat patients with EGFR T790M-positive non–small cell lung cancer (NSCLC) who have …
treat patients with EGFR T790M-positive non–small cell lung cancer (NSCLC) who have …