[PDF][PDF] Looking beneath the surface: the importance of subcortical structures in frontotemporal dementia

M Bocchetta, M Malpetti, EG Todd, JB Rowe… - Brain …, 2021 - academic.oup.com
Whilst initial anatomical studies of frontotemporal dementia focussed on cortical
involvement, the relevance of subcortical structures to the pathophysiology of frontotemporal …

Genuine memory deficits as assessed by the Free and Cued Selective Reminding Test (FCSRT) in the behavioural variant of frontotemporal dementia. A systematic …

L Macchitella, G Tosi, F Giaquinto, M Iaia, E Rizzi… - Neuropsychology …, 2023 - Springer
The current diagnostic criteria for the behavioural variant of frontotemporal dementia
(bvFTD) foresee a relative sparing of long-term memory. Although bvFTD patients were …

Proposed research criteria for prodromal behavioural variant frontotemporal dementia

MS Barker, RT Gottesman, M Manoochehri… - Brain, 2022 - academic.oup.com
At present, no research criteria exist for the diagnosis of prodromal behavioural variant
frontotemporal dementia (bvFTD), though early detection is of high research importance …

Progression of behavioral disturbances and neuropsychiatric symptoms in patients with genetic frontotemporal dementia

A Benussi, E Premi, S Gazzina, C Brattini… - JAMA Network …, 2021 - jamanetwork.com
Importance Behavioral disturbances are core features of frontotemporal dementia (FTD);
however, symptom progression across the course of disease is not well characterized in …

Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia

A Benussi, A Alberici, K Samra, LL Russell… - Alzheimer's & …, 2022 - Wiley Online Library
The presymptomatic stages of frontotemporal dementia (FTD) are still poorly defined and
encompass a long accrual of progressive biological (preclinical) and then clinical …

Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve

I Illán‐Gala, KB Casaletto… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction Biological sex is an increasingly recognized factor driving clinical and structural
heterogeneity in Alzheimer's disease, but its role in the behavioral variant of frontotemporal …

Neurodevelopmental effects of genetic frontotemporal dementia in young adult mutation carriers

E Finger, R Malik, M Bocchetta, K Coleman, C Graff… - Brain, 2023 - academic.oup.com
While frontotemporal dementia has been considered a neurodegenerative disease that
starts in mid-life or later, it is now clearly established that cortical and subcortical volume loss …

Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes

M Malpetti, PS Jones, KA Tsvetanov… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction Apathy adversely affects prognosis and survival of patients with frontotemporal
dementia (FTD). We test whether apathy develops in presymptomatic genetic FTD, and is …

Characterizing the Clinical Features and Atrophy Patterns of MAPT-Related Frontotemporal Dementia With Disease Progression Modeling

AL Young, M Bocchetta, LL Russell, RS Convery… - Neurology, 2021 - AAN Enterprises
Background and Objective Mutations in the MAPT gene cause frontotemporal dementia
(FTD). Most previous studies investigating the neuroanatomical signature of MAPT …

[HTML][HTML] Biomarkers in frontotemporal dementia: Current landscape and future directions

A Gifford, N Praschan, A Newhouse… - Biomarkers in …, 2023 - Elsevier
Frontotemporal dementia (FTD) is one of the most common neurodegenerative diseases,
encompassing a myriad of different, clinically distinct subtypes which all target the …