Persistent influence of maternal obesity on offspring health: Mechanisms from animal models and clinical studies

UD Wankhade, KM Thakali, K Shankar - Molecular and cellular …, 2016 - Elsevier
The consequences of excessive maternal weight and adiposity at conception for the
offspring are now well recognized. Maternal obesity increases the risk of overweight and …

Impact of pregravid obesity on maternal and fetal immunity: Fertile grounds for reprogramming

S Sureshchandra, NE Marshall… - Journal of leukocyte …, 2019 - academic.oup.com
Maternal pregravid obesity results in several adverse health outcomes during pregnancy,
including increased risk of gestational diabetes, preeclampsia, placental abruption, and …

[HTML][HTML] Maternal obesity impairs fetal cardiomyocyte contractile function in sheep

Q Wang, C Zhu, M Sun, R Maimaiti, SP Ford… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Obesity is a major public health problem worldwide. In the United States, one-third of women
of reproductive age are obese. Human studies show that maternal obesity (MO) predisposes …

Prenatal origins of postnatal variation in growth, development and productivity of ruminants

AW Bell, PL Greenwood - Animal Production Science, 2016 - CSIRO Publishing
This review provides an update on recent research into the effects of maternal nutrition on
fetal biology and the growth, development and productivity of progeny in postnatal life of …

The effects of poor maternal nutrition during gestation on postnatal growth and development of lambs

ML Hoffman, KN Peck, ME Forella, AR Fox… - Journal of animal …, 2016 - academic.oup.com
Poor maternal nutrition can affect the growth and development of offspring, which may lead
to negative consequences in adult life. We hypothesized that lambs born to poorly nourished …

Maternal diet-induced obesity and offspring cardiovascular health

HL Blackmore, SE Ozanne - … of developmental origins of health and …, 2013 - cambridge.org
It is widely recognized that environmental insults during adulthood including smoking, lack
of exercise and a poor diet increases an individual's risk of cardiovascular disease (CVD) …

Poor maternal nutrition during gestation in sheep reduces circulating concentrations of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in …

ML Hoffman, MA Rokosa, SA Zinn, TA Hoagland… - Domestic animal …, 2014 - Elsevier
To determine if poor maternal nutrition alters growth, body composition, circulating growth
factors, and expression of genes involved in the development of muscle and adipose of …

Effects of body condition score on the reproductive physiology of the broodmare: a review

SA Morley, JA Murray - Journal of Equine Veterinary Science, 2014 - Elsevier
The feeding management of broodmares is essential for breeding and successfully raising a
healthy foal. A feeding regime will depend on the breed of mare, her age, body condition …

Developmental programming of pediatric nonalcoholic fatty liver disease: redefining the “first hit”

MS Stewart, MJR Heerwagen… - Clinical Obstetrics and …, 2013 - journals.lww.com
The incidence of pediatric nonalcoholic fatty liver disease has increased dramatically, and
growing evidence indicates that the pathophysiology may be unique from the adult form …

Body mass index in parents and their adult offspring: A systematic review and meta‐analysis

J Zhang, GL Clayton, K Overvad, A Olsen… - Obesity …, 2024 - Wiley Online Library
Obesity may track across generations, due to genetics and shared family environmental
factors, or possibly intrauterine programming. However, many studies only assess …