We provide a comprehensive classification of the proteoglycan gene families and respective
protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular …

The extracellular matrix (ECM) proteoglycan, versican increases along with other ECM
versican binding molecules such as hyaluronan, tumor necrosis factor stimulated gene-6 …

Toll-like receptors (TLRs) are components of the innate immune system that respond to
exogenous infectious ligands (pathogen-associated molecular patterns, PAMPs) and …

Phagocytic receptors must diffuse laterally to become activated upon clustering by
multivalent targets. Receptor diffusion, however, can be obstructed by transmembrane …

Hyaluronan and versican are extracellular matrix (ECM) components that are enriched in the
provisional matrices that form during the early stages of development and disease. These …

Synthesis, deposition, and interactions of hyaluronan (HA) with its cellular receptor CD44
are crucial events that regulate the onset and progression of tumors. The intracellular …

Decorin, a prototype small leucine-rich proteoglycan, regulates a vast array of cellular
processes including collagen fibrillogenesis, wound repair, angiostasis, tumor growth, and …

The role of the host extracellular matrix (ECM) in infection tends to be neglected. However,
the complex interactions between invading pathogens, host tissues and immune cells occur …

The content of proteoglycans (PGs) is low in the extracellular matrix (ECM) of vascular
tissue, but increases dramatically in all phases of vascular disease. Early studies …

Trafficking of tissue dendritic cells (DCs) via lymph is critical for the generation of cellular
immune responses in draining lymph nodes (LNs). In the current study we found that DCs …