Genetic and biological drivers of prostate cancer disparities in Black men

J Gong, DM Kim, MR Freeman, H Kim, L Ellis… - Nature Reviews …, 2024 - nature.com
Black men with prostate cancer have historically had worse outcomes than white men with
prostate cancer. The causes of this disparity in outcomes are multi-factorial, but a potential …

Genetic Polymorphisms of the Telomerase Reverse Transcriptase Gene in Relation to Prostate Tumorigenesis, Aggressiveness and Mortality: A Cross-Ancestry …

Y Zhan, X Ruan, J Liu, D Huang, J Huang, J Huang… - Cancers, 2023 - mdpi.com
Simple Summary Mutation in telomerase reverse transcriptase (TERT) has been reportedly
related to risks of prostate cancer (PCa). However, prior genome-wide association studies …

[HTML][HTML] Improving genetic risk modeling of dementia from real-world data in underrepresented populations

M Fu, L Valiente-Banuet, SS Wadhwa, B Pasaniuc… - medRxiv, 2024 - ncbi.nlm.nih.gov
BACKGROUND: Genetic risk modeling for dementia offers significant benefits, but studies
based on real-world data, particularly for underrepresented populations, are limited …

[HTML][HTML] Improving genetic risk modeling of dementia from real-world data in underrepresented populations

T Chang, M Fu, L Valiente-Banuet, S Wadhwa… - Research …, 2024 - ncbi.nlm.nih.gov
BACKGROUND: Genetic risk modeling for dementia offers significant benefits, but studies
based on real-world data, particularly for underrepresented populations, are limited …

The Combined Effect of Polygenic Risk Score and Prostate Health Index in Chinese Men Undergoing Prostate Biopsy

X Ruan, D Huang, J Huang, J Huang, Y Zhan… - Journal of Clinical …, 2023 - mdpi.com
To date, the combined effect of polygenic risk score (PRS) and prostate health index (phi) on
PCa diagnosis in men undergoing prostate biopsy has never been investigated. A total of …