The combination of antibiotic and non-antibiotic compounds improves antibiotic efficacy against multidrug-resistant bacteria

G Xiao, J Li, Z Sun - International Journal of Molecular Sciences, 2023 - mdpi.com
Bacterial antibiotic resistance, especially the emergence of multidrug-resistant (MDR)
strains, urgently requires the development of effective treatment strategies. It is always of …

Anti-Pseudomonas aeruginosa activity of natural antimicrobial peptides when used alone or in combination with antibiotics

X Chen, S Su, Y Yan, L Yin, L Liu - Frontiers in Microbiology, 2023 - frontiersin.org
The World Health Organization has recently published a list of 12 drug-resistant bacteria that
posed a significant threat to human health, and Pseudomonas aeruginosa (P. aeruginosa) …

Synergy between Human Peptide LL-37 and Polymyxin B against Planktonic and Biofilm Cells of Escherichia coli and Pseudomonas aeruginosa

KE Ridyard, M Elsawy, D Mattrasingh, D Klein… - Antibiotics, 2023 - mdpi.com
The rise in antimicrobial resistant bacteria is limiting the number of effective treatments for
bacterial infections. Escherichia coli and Pseudomonas aeruginosa are two of the …

Human Mesenchymal Stem Cell (hMSC) Donor Potency Selection for the “First in Cystic Fibrosis” Phase I Clinical Trial (CEASE-CF)

TL Bonfield, MT Sutton, DR Fletcher, J Reese-Koc… - Pharmaceuticals, 2023 - mdpi.com
Human Mesenchymal Stem Cell (hMSC) immunotherapy has been shown to provide both
anti-inflammatory and anti-microbial effectiveness in a variety of diseases. The clinical …

PAM-1: an antimicrobial peptide with promise against ceftazidime-avibactam resistant Escherichia coli infection

Y Han, Y Zhang, X Zhang, Z Huang, J Kong… - Frontiers in …, 2024 - frontiersin.org
Introduction Antibiotic misuse and overuse have led to the emergence of carbapenem-
resistant bacteria. The global spread of resistance to the novel antibiotic combination …

LL37-Derived Fragments Improve the Antibacterial Potential of Penicillin G and Ampicillin against Methicillin-Resistant Staphylococcus aureus

W Han, TA Camesano - Antibiotics, 2023 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) infections are a severe threat to public
health. Antimicrobial peptides (AMPs) are novel and potential antimicrobials with specific …

[HTML][HTML] Octominin: An antimicrobial peptide with antibacterial and anti-inflammatory activity against carbapenem-resistant Escherichia coli both in vitro and in vivo

J Kong, Y Wang, Y Han, H Zhou, Z Huang… - Journal of Global …, 2023 - Elsevier
Objectives The emergence of carbapenem-resistant Escherichia coli (CREC) is a global
concern as its prevalence restricts treatment options and poses a considerable threat to …

[PDF][PDF] Synergistic Combinations between Human-Derived Antimicrobial Peptides and Traditional Antibiotics against Escherichia coli

N Watkins - 2023 - digital.wpi.edu
The growing prevalence of antimicrobial resistance to clinical antibiotic treatments has been
declared a healthcare crisis by several national and international public health agencies …