Mechanisms of cancer cell death induction by paclitaxel: an updated review

S Zhao, Y Tang, R Wang, M Najafi - Apoptosis, 2022 - Springer
Chemoresistance of cancer cells is a major problem in treating cancer. Knowledge of how
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …

Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery

F Davodabadi, SF Sajjadi, M Sarhadi… - European Journal of …, 2023 - Elsevier
Conventional chemotherapy, one of the most widely used cancer treatment methods, has
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …

[HTML][HTML] A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3

Y Zhou, Y Shao, W Hu, J Zhang, Y Shi… - Cell Death & …, 2023 - nature.com
Although radiotherapy is an essential modality in the treatment of colorectal cancer (CRC),
the incidence of radioresistance remains high clinically. Long noncoding RNAs (lncRNAs) …

[HTML][HTML] Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches

B Jahangiri, AK Saei, PO Obi, N Asghari… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Exosomal release pathway and autophagy together maintain homeostasis and survival of
cells under stressful conditions. Autophagy is a catabolic process through which cell entities …

[HTML][HTML] Epigenetic regulation of autophagy in gastrointestinal cancers

S Ghavami, M Zamani, M Ahmadi, M Erfani… - … et Biophysica Acta (BBA …, 2022 - Elsevier
The development of novel therapeutic approaches is necessary to manage gastrointestinal
cancers (GICs). Considering the effective molecular mechanisms involved in tumor growth …

[HTML][HTML] Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response

M Ashrafizadeh, MDA Paskeh, S Mirzaei… - Journal of Experimental …, 2022 - Springer
Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …

[HTML][HTML] 6‑Gingerol suppresses cell viability, migration and invasion via inhibiting EMT, and inducing autophagy and ferroptosis in LPS‑stimulated and LPS …

CM Liu, L An, Z Wu, AJ Ouyang, M Su… - Oncology …, 2022 - spandidos-publications.com
Gingerol is a bioactive compound isolated from Zingiber officinale. 6‑Gingerol has been
shown to have anticancer effects in numerous types of cancer cell. The mechanisms …

Novel platinum nanoclusters activate PI3K/AKT/mTOR signaling pathway-mediated autophagy for cisplatin-resistant ovarian cancer therapy

M Zhang, H Yue, X Huang, J Wang, Z Li… - ACS Applied Materials …, 2022 - ACS Publications
Platinum (Pt)-based chemotherapy drugs such as cisplatin are the first line and core options
for the treatment of ovarian cancer (OC), while cisplatin resistance has a worse prognosis …

A multifunctional nanodiamond-based nanoplatform for the enhanced mild-temperature photothermal/chemo combination therapy of triple negative breast cancer via …

X Cui, Z Liang, J Lu, X Wang, F Jia, Q Hu, X Xiao… - Nanoscale, 2021 - pubs.rsc.org
Owing to its aggressive biological behavior, the lack of specific targets, and the strong
therapeutic resistance of triple negative breast cancer (TNBC), current therapeutic strategies …

[HTML][HTML] Personalized drug screening in patient-derived organoids of biliary tract cancer and its clinical application

X Ren, M Huang, W Weng, Y Xie, Y Wu, S Zhu… - Cell Reports …, 2023 - cell.com
Patients with biliary tract cancer (BTC) show different responses to chemotherapy, and there
is no effective way to predict chemotherapeutic response. We have generated 61 BTC …