Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …

The treatment of chronic wounds is a major challenge in regenerative medicine, and
angiogenesis is known to be critical for chronic wound healing. Hot springs with temperature …

Abstract 3D culture of cells in designer biomaterial matrices provides a biomimetic cellular
microenvironment and can yield critical insights into cellular behaviours not available from …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

The recurrence of cutaneous cancer and multidrug-resistant (MDR) bacteria infected-wound
healing after surgical excision remains a great challenge for both clinic and research. In this …

Regenerative medicine holds the promise of engineering functional tissues or organs to
heal or replace abnormal and necrotic tissues/organs, offering hope for filling the gap …

Growth factors are critical molecules for tissue repair and regeneration. Therefore,
recombinant growth factors have raised a lot of hope for regenerative medicine applications …

Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …

Impaired diabetic wound healing represents a devastating and rapidly growing clinical
problem associated with high morbidity, mortality, and recurrence rates. Engineering …