[HTML][HTML] Chemotherapy-induced constipation and diarrhea: pathophysiology, current and emerging treatments

RM McQuade, V Stojanovska, R Abalo… - Frontiers in …, 2016 - frontiersin.org
Gastrointestinal (GI) side-effects of chemotherapy are a debilitating and often overlooked
clinical hurdle in cancer management. Chemotherapy-induced constipation (CIC) and …

Cancer-associated malnutrition

VE Baracos - European journal of clinical nutrition, 2018 - nature.com
We know the susceptibility of patients with different cancers to malnutrition, albeit that there
are not widespread demographics. While cancer statistics are reported in most jurisdictions …

[HTML][HTML] The clinical value of nutritional care before and during active cancer treatment

G Aprile, D Basile, R Giaretta, G Schiavo, N La Verde… - Nutrients, 2021 - mdpi.com
Malnutrition and muscle wasting are frequently reported in cancer patients, either linked to
the tumor itself or caused by oncologic therapies. Understanding the value of nutritional care …

[HTML][HTML] Nutritional Support in Cancer patients: update of the Italian Intersociety Working Group practical recommendations

R Caccialanza, P Cotogni, E Cereda, P Bossi… - Journal of …, 2022 - ncbi.nlm.nih.gov
Malnutrition is a frequent problem in cancer patients, which leads to prolonged and repeated
hospitalizations, increased treatment-related toxicity, reduced response to cancer treatment …

[HTML][HTML] Irinotecan (CPT-11) chemotherapy alters intestinal microbiota in tumour bearing rats

XB Lin, LA Dieleman, A Ketabi, I Bibova, MB Sawyer… - PloS one, 2012 - journals.plos.org
Intestinal microbiota mediate toxicity of irinotecan (CPT-11) cancer therapies and cause
systemic infection after CPT-11-induced loss of barrier function. The intestinal microbiota …

[HTML][HTML] Relevance of dietary supplement use in gastrointestinal-Cancer-associated Cachexia

SL Yoon, O Grundmann - Nutrients, 2023 - mdpi.com
Cancer cachexia is a multi-organ syndrome with unintentional weight loss, sarcopenia, and
systemic inflammation. Gastrointestinal (GI) cancer patients are more susceptible to …

Animal models of chemotherapy-induced mucositis: translational relevance and challenges

PT Sangild, RL Shen… - American Journal of …, 2018 - journals.physiology.org
Chemotherapy for cancer patients induces damaging tissue reactions along the epithelium
of the gastrointestinal tract (GIT). This chemotherapy-induced mucositis (CIM) is a serious …

Relationship between the gut microbiome and systemic chemotherapy

SM Ervin, SV Ramanan, AP Bhatt - Digestive diseases and sciences, 2020 - Springer
The intestinal microbiome encodes vast metabolic potential, and multidisciplinary
approaches are enabling a mechanistic understanding of how bacterial enzymes impact the …

Pharmacological strategies in lung cancer‐induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness

A Chacon‐Cabrera, C Fermoselle… - Journal of cellular …, 2014 - Wiley Online Library
Cachexia is a relevant comorbid condition of chronic diseases including cancer.
Inflammation, oxidative stress, autophagy, ubiquitin–proteasome system, nuclear factor (NF) …

Can prebiotics and probiotics improve therapeutic outcomes for undernourished individuals?

PO Sheridan, LB Bindels, DM Saulnier, G Reid, E Nova… - 2014 - Taylor & Francis
It has become clear in recent years that the human intestinal microbiota plays an important
role in maintaining health and thus is an attractive target for clinical interventions. Scientists …