Globally, rates of ESBL-producing Enterobacteriaceae are rising. We undertook a literature
review, and present the temporal trends in bla CTX-M epidemiology, showing that bla CTX …

Extended spectrum beta-lactamases (ESBLs) are defined as enzymes produced by certain
bacteria that are able to hydrolyze extended spectrum cephalosporin. They are therefore …

Extended-spectrum β-lactamases (ESBLs) are a rapidly evolving group of β-lactamases
which share the ability to hydrolyze third-generation cephalosporins and aztreonam yet are …

Alexander Fleming's discovery of penicillin heralded an age of antibiotic development and
healthcare advances that are premised on the ability to prevent and treat bacterial infections …

Extended spectrum β-lactamase (ESBL)-producing organisms pose unique challenges to
clinical microbiologists, clinicians, infection control professionals and antibacterial-discovery …

Bacteremia remains a major cause of life-threatening complication in patients with cancer.
Significant changes in the spectrum of microorganisms isolated from blood culture have …

BACKGROUNDDespite a reported worldwide increase, the incidence of extended-spectrum
β-lactamase (ESBL) Escherichia coli and Klebsiella infections in the United States is …

The prevalence of extended-spectrum β-lactamase (ESBL) production by Klebsiella
pneumonia approaches 50% in some countries, with particularly high rates in eastern …

Extended spectrum β‐lactamases (ESBLs) are enzymes produced by a variety of Gram
negative bacteria which confer an increased resistance to commonly used antibiotics. They …

Background: Escherichia coli is the leading cause of urinary tract, ear, wound and other
infections in humans. Increasing rates of antimicrobial resistance among E. coli is a growing …