[HTML][HTML] GABAergic inhibitory interneuron deficits in Alzheimer's disease: implications for treatment

Y Xu, M Zhao, Y Han, H Zhang - Frontiers in neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by severe
cognitive deficits and pathologically by amyloid plaques, neuronal loss, and neurofibrillary …

[HTML][HTML] Naturally occurring acetylcholinesterase inhibitors and their potential use for Alzheimer's disease therapy

TC Santos, TM Gomes, BAS Pinto… - Frontiers in …, 2018 - frontiersin.org
Alzheimer's disease (AD) is a main cause of dementia, accounting for up to 75% of all
dementia cases. Pathophysiological processes described for AD progression involve …

[HTML][HTML] Advances on plant extracts and phytocompounds with acetylcholinesterase inhibition activity for possible treatment of Alzheimer's disease

R Taqui, M Debnath, S Ahmed, A Ghosh - Phytomedicine plus, 2022 - Elsevier
Background Alzheimer's disease (AD) is a neurodegenerative disease caused by the
formation of amyloid-beta (Aβ) plaques and neurofibrillary tangles. Acetylcholinesterase …

[HTML][HTML] Acetylcholinesterase inhibitors from southern African plants: An overview of ethnobotanical, pharmacological potential and phytochemical research including …

NA Masondo, GI Stafford, AO Aremu… - South African journal of …, 2019 - Elsevier
The review focuses on acetylcholinesterase (AChE) inhibition of extracts and compounds
from southern African plants. We provide a detailed inventory of southern African plants …

[HTML][HTML] Potential of naturally derived alkaloids as multi-targeted therapeutic agents for neurodegenerative diseases

YR Kong, KC Tay, YX Su, CK Wong, WN Tan, KY Khaw - Molecules, 2021 - mdpi.com
Alkaloids are a class of secondary metabolites that can be derived from plants, fungi and
marine sponges. They are widely known as a continuous source of medicine for the …

Beyond the approved: target sites and inhibitors of bacterial RNA polymerase from bacteria and fungi

SH Kirsch, FPJ Haeckl, R Müller - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 2016 to 2022 RNA polymerase (RNAP) is the central enzyme in bacterial gene
expression representing an attractive and validated target for antibiotics. Two well-known …

[HTML][HTML] Traditional Chinese medicine for anti-Alzheimer's disease: berberine and evodiamine from Evodia rutaecarpa

Z Fang, Y Tang, J Ying, C Tang, Q Wang - Chinese medicine, 2020 - Springer
Alzheimer's disease (AD) is one of the most common diseases in elderly people with a high
incidence of dementia at approximately 60–80%. The pathogenesis of AD was quite …

[HTML][HTML] Natural polysaccharides as preventive and therapeutic horizon for neurodegenerative diseases

M Dhahri, M Alghrably, HA Mohammed, SL Badshah… - Pharmaceutics, 2021 - mdpi.com
Neurodegenerative diseases are a serious and widespread global public health burden
amongst aging populations. The total estimated worldwide global cost of dementia was US 818billionin2015andhasbeenprojectedtoris …

Ocular manifestations of Alzheimer's and other neurodegenerative diseases: the prospect of the eye as a tool for the early diagnosis of Alzheimer's disease

P Colligris, MJ Perez de Lara… - Journal of …, 2018 - Wiley Online Library
Dementia, including Alzheimer's disease (AD), is a major disorder, leading to several ocular
manifestations amongst the elderly population. These visual disorders may be due to retinal …

Application of quercetin in neurological disorders: From nutrition to nanomedicine

E Amanzadeh, A Esmaeili, S Rahgozar… - Reviews in the …, 2019 - degruyter.com
Quercetin is a polyphenolic flavonoid, which is frequently found in fruits and vegetables. The
antioxidant potential of quercetin has been studied from subcellular compartments, that is …