With rapidly changing ecology, urbanization, climate change, increased travel and fragile
public health systems, epidemics will become more frequent, more complex and harder to …

The evidence for an association between coxsackievirus B (CVB) infection, pancreatic islet
autoimmunity, and clinical type 1 diabetes is increasing. Results from prospective cohorts …

In June 2022, poliovirus was confirmed in an unvaccinated immunocompetent adult resident
of New York hospitalized with flaccid lower limb weakness. Vaccine-derived poliovirus type …

To explore kinship practices at chambered tombs in Early Neolithic Britain, here we
combined archaeological and genetic analyses of 35 individuals who lived about 5,700 …

Background Hand, foot, and mouth disease is a common childhood illness caused by
enteroviruses. Increasingly, the disease has a substantial burden throughout east and …

The attenuated oral poliovirus vaccine (OPV) has many properties favoring its use in polio
eradication: ease of administration, efficient induction of intestinal immunity, induction of …

Although there have been no cases of serotype 2 wild poliovirus for more than 20 years,
transmission of serotype 2 vaccine-derived poliovirus (VDPV2) and associated paralytic …

The COVID-19 pandemic has ignited interest in age-specific manifestations of infection but
surprisingly little is known about relative severity of infectious disease between the extremes …

The cell danger response (CDR) is the evolutionarily conserved metabolic response that
protects cells and hosts from harm. It is triggered by encounters with chemical, physical, or …

Israel experienced an outbreak of wild poliovirus type 1 (WPV1) in 2013–2014, detected
through environmental surveillance of the sewage system. No cases of acute flaccid …