SGLT2 (sodium-glucose cotransporter 2) inhibitors produce a distinctive pattern of benefits
on the evolution and progression of cardiomyopathy and nephropathy, which is …

Given that the increase in the aging population has grown into one of the largest public
health issues, inflammation and oxidative stress, which are closely associated with the aging …

Trastuzumab (TZM) is commonly used for target therapy in breast cancer patients with high
HER2 although the cardiotoxicity restricts its clinical usage. DNA damage and ferroptosis …

Diabetic patients are frequently affected by coronary microvascular dysfunction (CMD), a
condition consisting of a combination of altered vasomotion and long-term structural change …

Myocardial damage is the most serious pathological consequence of cardiovascular
diseases and an important reason for their high mortality. In recent years, because of the …

Flap necrosis, the most prevalent postoperative complication of reconstructive surgery, is
significantly associated with ischaemia–reperfusion injury. Recent research indicates that …

Recent evidence shows a close link between Parkinson's disease (PD) and cardiac
dysfunction with limited treatment options. Mitophagy plays a crucial role in the control of …

Diabetic cardiomyopathy is a chronic cardiovascular complication caused by diabetes that is
characterized by changes in myocardial structure and function, ultimately leading to heart …

Background Myocardial microvascular injury is the key event in early diabetic heart disease.
The injury of myocardial microvascular endothelial cells (CMECs) is the main cause and …

Aims: Myocardial ischemia–reperfusion (I/R) injury facilitates cardiomyocyte death and
endangers human health. N6-methyladenosine (m6A) methylation plays a critical role in …