Elucidating the molecular mechanism of autophagy was a landmark in understanding not
only the physiology of cells and tissues, but also the pathogenesis of diverse diseases …

Doxorubicin induces myocardial injury and fibrosis. Still, no effective interventions are
available. AP39 is an H 2 S donor that explicitly targets mitochondria. This study investigated …

Heart failure occurs because of various cardiovascular pathologies, such as coronary artery
disease or cardiorenal syndrome, eventually reaching end‐stage disease. Various factors …

Autophagy is a process of self-renewal in cells, which not only provides the necessary
nutrients for cells, but also clears necrotic organelles. Autophagy disorders are closely …

Abstract Sodium-glucose co-transporter-2 inhibitors are used in the treatment of diabetes but
are also emerging as cardioprotective agents in heart diseases even in the absence of type …

As an essential trace element for organisms, zinc participates in various physiological
processes, such as RNA transcription, DNA replication, cell proliferation, and cell …

Mitochondria, the most crucial energy-generating organelles in eukaryotic cells, play a
pivotal role in regulating energy metabolism. However, their significance extends beyond …

Background Zishenhuoxue decoction (ZSHX), a Chinese herbal medicine, exhibits
myocardial and vascular endothelial protective properties. The intricate regulatory …

Myocardial reperfusion injury occurs when blood flow is restored after ischemia, an essential
process to salvage ischemic tissue. However, this phenomenon is intricate, characterized by …

Background Type 2 diabetes mellitus (T2DM) induced diabetes-associated cognitive
dysfunction (DACD) that seriously affects the self-management of T2DM patients, is currently …