Gold nanoparticles as a potent radiosensitizer: A transdisciplinary approach from physics to patient

S Penninckx, AC Heuskin, C Michiels, S Lucas - Cancers, 2020 - mdpi.com
Over the last decade, a growing interest in the improvement of radiation therapies has led to
the development of gold-based nanomaterials as radiosensitizer. Although the …

Mechanisms of nanoparticle radiosensitization

I Kempson - Wiley Interdisciplinary Reviews: Nanomedicine …, 2021 - Wiley Online Library
Metal‐based nanoparticles applied to potentiating the effects of radiotherapy have drawn
significant attention from the research community and are now available clinically. By …

Impact of superparamagnetic iron oxide nanoparticles on in vitro and in vivo radiosensitisation of cancer cells

E Russell, V Dunne, B Russell, H Mohamud, M Ghita… - Radiation …, 2021 - Springer
Purpose The recent implementation of MR-Linacs has highlighted theranostic opportunities
of contrast agents in both imaging and radiotherapy. There is a lack of data exploring the …

Intercomparison of radiosensitization induced by gold and iron oxide nanoparticles in human glioblastoma cells irradiated by 6 MV photons

DB Guerra, EMN Oliveira, AR Sonntag, P Sbaraine… - Scientific Reports, 2022 - nature.com
In this work, an intercomparison of sensitization effects produced by gold (GNP) and dextran-
coated iron oxide (SPION-DX) nanoparticles in M059J and U87 human glioblastoma cells …

Advances in the mechanistic understanding of iron oxide nanoparticles' radiosensitizing properties

I Ternad, S Penninckx, V Lecomte, T Vangijzegem… - Nanomaterials, 2023 - mdpi.com
Among the plethora of nanosystems used in the field of theranostics, iron oxide
nanoparticles (IONPs) occupy a central place because of their biocompatibility and magnetic …

Condensed Matter Systems Exposed to Radiation: Multiscale Theory, Simulations, and Experiment

AV Solov'yov, AV Verkhovtsev, NJ Mason… - Chemical …, 2024 - ACS Publications
This roadmap reviews the new, highly interdisciplinary research field studying the behavior
of condensed matter systems exposed to radiation. The Review highlights several recent …

An overview of the intracellular localization of high-Z nanoradiosensitizers

M Varzandeh, S Labbaf, J Varshosaz… - Progress in Biophysics and …, 2022 - Elsevier
Radiation therapy (RT) is a method commonly used for cancer treatment worldwide.
Commonly, RT utilizes two routes for combating cancers: 1) high-energy radiation to …

Proton therapy, magnetic nanoparticles and hyperthermia as combined treatment for pancreatic BxPC3 tumor cells

F Brero, P Calzolari, M Albino, A Antoccia, P Arosio… - Nanomaterials, 2023 - mdpi.com
We present an investigation of the effects on BxPC3 pancreatic cancer cells of proton
therapy combined with hyperthermia, assisted by magnetic fluid hyperthermia performed …

Potentials of Bismuth-Based Nanoparticles and Baicalein Natural Compounds as Radiosensitizers in Cancer Radiotherapy: a Review

NNT Sisin, WN Rahman - BioNanoScience, 2023 - Springer
Radiotherapy treatment on cancer patients has the limitation of the possible side effects to
the unrelated healthy tissues. Hence, radiosensitizers have been utilized to enhance the …

Radiation therapy-activated nanoparticle and immunotherapy: The next milestone in oncology?

S Penninckx, J Thariat, C Mirjolet - … Review of Cell and Molecular Biology, 2023 - Elsevier
Radiotherapy (RT) is a fundamental treatment at the locoregional or oligometastatic stages
of cancer. In various tumors, RT effects may be optimized using synergistic combinations …