Updates on obesity and the obesity paradox in cardiovascular diseases

AW Tutor, CJ Lavie, S Kachur, RV Milani… - Progress in …, 2023 - Elsevier
The prevalence of obesity has reached pandemic proportions worldwide and certainly in the
United States. Obesity is a well-established independent risk factor for development of many …

Stress and obesity: are there more susceptible individuals?

ES Van der Valk, M Savas, EFC van Rossum - Current obesity reports, 2018 - Springer
Abstract Purpose of Review Stress has long been suspected to be interrelated to
(abdominal) obesity. However, interindividual differences in this complex relationship exist …

[HTML][HTML] Profound perturbation of the metabolome in obesity is associated with health risk

ET Cirulli, L Guo, CL Swisher, N Shah, L Huang… - Cell metabolism, 2019 - cell.com
Obesity is a heterogeneous phenotype that is crudely measured by body mass index (BMI).
There is a need for a more precise yet portable method of phenotyping and categorizing risk …

Hypothalamic-pituitary-adrenal axis dysregulation and cortisol activity in obesity: a systematic review

ACI Rodriguez, ES Epel, ML White, EC Standen… - …, 2015 - Elsevier
Background Although there is substantial evidence of differential hypothalamic-pituitary-
adrenal (HPA) axis activity in both generalized and abdominal obesity, consistent trends in …

Interplay between the gut-brain axis, obesity and cognitive function

A Agustí, MP García-Pardo, I López-Almela… - Frontiers in …, 2018 - frontiersin.org
Obesity continues to be one of the major public health problems due to its high prevalence
and co-morbidities. Common co-morbidities not only include cardiometabolic disorders but …

Effects of phytosomal curcumin on anthropometric parameters, insulin resistance, cortisolemia and non-alcoholic fatty liver disease indices: a double-blind, placebo …

AFG Cicero, A Sahebkar, F Fogacci, M Bove… - European journal of …, 2020 - Springer
Purpose Curcumin has shown to exert a positive impact on human glucose metabolism,
even if its bioavailability is usually very low. The present study aimed to explore the effect of …

Towards a multidisciplinary approach to understand and manage obesity and related diseases

SC Bischoff, Y Boirie, T Cederholm, M Chourdakis… - Clinical nutrition, 2017 - Elsevier
Overnutrition and sedentary lifestyle result in overweight or obesity defined as abnormal or
excessive fat accumulation that may impair health. According to the WHO, the worldwide …

Glucocorticoid sensitivity in health and disease

RA Quax, L Manenschijn, JW Koper… - Nature Reviews …, 2013 - nature.com
Glucocorticoids regulate many physiological processes and have an essential role in the
systemic response to stress. For example, gene transcription is modulated by the …

New insights into the role of insulin and hypothalamic-pituitary-adrenal (HPA) Axis in the metabolic syndrome

JA Janssen - International journal of molecular sciences, 2022 - mdpi.com
Recent data suggests that (pre) diabetes onset is preceded by a period of hyperinsulinemia.
Consumption of the “modern” Western diet, over-nutrition, genetic background, decreased …

The association between psychological stress and metabolic syndrome: A systematic review and meta‐analysis

W Kuo, LC Bratzke, LD Oakley, F Kuo, H Wang… - Obesity …, 2019 - Wiley Online Library
Literature suggests that occupational stress is associated with a higher risk of metabolic
syndrome; yet less is known whether other sources of stress have similar effects. This review …