Carbohydrates are fundamental molecules involved in nearly all aspects of lives, such as
being involved in formating the genetic and energy materials, supporting the structure of …

Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …

Heparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic
backbone. Due to its fascinating chemical and physical properties, nontoxicity …

Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …

Heparin, the most widely used anticoagulant drug, is mainly acquired from livestock.
Variable structures and contaminations of other glycosaminoglycans of animal-sourced …

Heparan sulfate (HS) polysaccharides are master regulators of diverse biological processes
via sulfated motifs that can recruit specific proteins. 3-O-sulfation of HS/heparin is crucial for …

Highlights•Oral route of administration is the preferred route for drug delivery.•Dosage form
designing plays an essential role in oral peptide delivery.•Preclinical and clinical aspects of …

The pandemic coronavirus disease 2019 (COVID-19), caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading globally …

Owing to the high mortality and the spread rate, the infectious disease caused by SARS-CoV-
2 has become a major threat to public health and social economy, leading to over 70 million …

Heparan sulfate (HS) has multifaceted biological activities. To date, no libraries of HS
oligosaccharides bearing systematically varied sulfation structures are available owing to …