[HTML][HTML] Injectable, anti-inflammatory and conductive hydrogels based on graphene oxide and diacerein-terminated four-armed polyethylene glycol for spinal cord …
K Zhang, J Li, J Jin, J Dong, L Li, B Xue, W Wang… - Materials & Design, 2020 - Elsevier
Patients with spinal cord injury (SCI) often suffer from permanent disabilities because of the
low regeneration ability of adult axons. Hydrogels can serve as the scaffolding materials to …
low regeneration ability of adult axons. Hydrogels can serve as the scaffolding materials to …
[HTML][HTML] Natural compounds for SIRT1-mediated oxidative stress and neuroinflammation in stroke: A potential therapeutic target in the future
C Fang, H Xu, L Yuan, Z Zhu, X Wang, Y Liu… - … Medicine and Cellular …, 2022 - hindawi.com
Stroke is a fatal cerebral vascular disease with a high mortality rate and substantial
economic and social costs. ROS production and neuroinflammation have been implicated in …
economic and social costs. ROS production and neuroinflammation have been implicated in …
[HTML][HTML] Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation, blood-brain barrier damage and brain …
Á Dénes, S Ferenczi, KJ Kovács - Journal of neuroinflammation, 2011 - Springer
Background Systemic inflammation impairs outcome in stroke patients and experimental
animals via mechanisms which are poorly understood. Circulating inflammatory mediators …
animals via mechanisms which are poorly understood. Circulating inflammatory mediators …
[HTML][HTML] Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus
K Chu, B Yin, J Wang, G Peng, H Liang, Z Xu… - Journal of …, 2012 - Springer
Background Neuroinflammation plays an important role in cerebral ischemia/reperfusion
(I/R) injury. The P2X7 receptor (P2X7R) has been reported to be involved in the …
(I/R) injury. The P2X7 receptor (P2X7R) has been reported to be involved in the …
Mesenchymal stem cell‐based treatments for stroke, neural trauma, and heat stroke
YCY Hsuan, CH Lin, CP Chang, MT Lin - Brain and behavior, 2016 - Wiley Online Library
Background Mesenchymal stem cell (MSC) transplantation has been reported to improve
neurological function following neural injury. Many physiological and molecular …
neurological function following neural injury. Many physiological and molecular …
Piperine suppresses cerebral ischemia–reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat …
The pathophysiological mechanisms leading to neuronal injury in middle cerebral artery
occlusion (MCAO) model of cerebral stroke are complex and multifactorial that form the …
occlusion (MCAO) model of cerebral stroke are complex and multifactorial that form the …
[HTML][HTML] Molecular mechanisms of neuroimmune crosstalk in the pathogenesis of stroke
Stroke disrupts the homeostatic balance within the brain and is associated with a significant
accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central …
accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central …
Memory deficits and hippocampal inflammation in cerebral hypoperfusion and reperfusion in male rats: Neuroprotective role of vanillic acid
Ischemic stroke is one of the leading causes of neurological deterioration and mortality
worldwide. Neuroprotective strategies are being investigated to minimize cognitive deficits …
worldwide. Neuroprotective strategies are being investigated to minimize cognitive deficits …
Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin-1–induced mechanisms
Neuroimmune interactions may contribute to severe pain and regional inflammatory and
autonomic signs in complex regional pain syndrome (CRPS), a posttraumatic pain disorder …
autonomic signs in complex regional pain syndrome (CRPS), a posttraumatic pain disorder …
Delayed administration of interleukin-1 receptor antagonist reduces ischemic brain damage and inflammation in comorbid rats
Many neuroprotective agents have been effective in experimental stroke, yet few have
translated into clinical application. One reason for this may be failure to consider clinical …
translated into clinical application. One reason for this may be failure to consider clinical …