Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions
Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …
Aging and neurodegenerative disease: is the adaptive immune system a friend or foe?
K Mayne, JA White, CE McMurran, FJ Rivera… - Frontiers in aging …, 2020 - frontiersin.org
Neurodegenerative diseases of the central nervous system (CNS) are characterized by
progressive neuronal death and neurological dysfunction, leading to increased disability …
progressive neuronal death and neurological dysfunction, leading to increased disability …
The role of gamma-delta T cells in diseases of the central nervous system
J Wo, F Zhang, Z Li, C Sun, W Zhang… - Frontiers in …, 2020 - frontiersin.org
Gamma-delta (γδ) T cells are a subset of T cells that promote the inflammatory responses of
lymphoid and myeloid lineages, and are especially vital to the initial inflammatory and …
lymphoid and myeloid lineages, and are especially vital to the initial inflammatory and …
Post-traumatic epilepsy and comorbidities: advanced models, molecular mechanisms, biomarkers, and novel therapeutic interventions
Post-traumatic epilepsy (PTE) is one of the most devastating long-term, network
consequences of traumatic brain injury (TBI). There is currently no approved treatment that …
consequences of traumatic brain injury (TBI). There is currently no approved treatment that …
Multipotential and systemic effects of traumatic brain injury
Traumatic brain injury (TBI) is one of the leading causes of disability and mortality of people
at all ages. Biochemical, cellular and physiological events that occur during primary injury …
at all ages. Biochemical, cellular and physiological events that occur during primary injury …
Overview of traumatic brain injury: an immunological context
D Nizamutdinov, LA Shapiro - Brain sciences, 2017 - mdpi.com
Traumatic brain injury (TBI) afflicts people of all ages and genders, and the severity of injury
ranges from concussion/mild TBI to severe TBI. Across all spectrums, TBI has wide-ranging …
ranges from concussion/mild TBI to severe TBI. Across all spectrums, TBI has wide-ranging …
[HTML][HTML] White matter damage after traumatic brain injury: a role for damage associated molecular patterns
Traumatic brain injury (TBI) is a leading cause of mortality and long-term morbidity
worldwide. Despite decades of pre-clinical investigation, therapeutic strategies focused on …
worldwide. Despite decades of pre-clinical investigation, therapeutic strategies focused on …
Neuropathophysiological mechanisms and treatment strategies for post-traumatic epilepsy
S Sharma, G Tiarks, J Haight… - Frontiers in molecular …, 2021 - frontiersin.org
Traumatic brain injury (TBI) is a leading cause of death in young adults and a risk factor for
acquired epilepsy. Severe TBI, after a period of time, causes numerous neuropsychiatric and …
acquired epilepsy. Severe TBI, after a period of time, causes numerous neuropsychiatric and …
Brain trauma, glucocorticoids and neuroinflammation: dangerous liaisons for the hippocampus
IG Komoltsev, NV Gulyaeva - Biomedicines, 2022 - mdpi.com
Glucocorticoid-dependent mechanisms of inflammation-mediated distant hippocampal
damage are discussed with a focus on the consequences of traumatic brain injury. The …
damage are discussed with a focus on the consequences of traumatic brain injury. The …
Platelet-to-lymphocyte ratio predicts short-term mortality in patients with moderate to severe traumatic brain injury
W Li, W Deng - Scientific Reports, 2022 - nature.com
An easily accessible biomarker with good diagnostic power for patients with traumatic brain
injury (TBI) was needed to predict the short-term mortality. Studies have shown that platelet …
injury (TBI) was needed to predict the short-term mortality. Studies have shown that platelet …