This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Chemokines are a large family of small secreted proteins that have fundamental roles in
organ development, normal physiology, and immune responses upon binding to their …

Inflammation drives coronary artery disease and atherosclerosis implications. Lipoprotein
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …

Atherosclerosis is a chronic inflammatory disease and the pathological basis of many fatal
cardiovascular diseases. Macrophages, the main inflammatory cells in atherosclerotic …

Background Acute myocardial infarction (AMI) can occur in patients with atherosclerotic
disease, with or without plaque rupture. Previous studies have indicated a set of immune …

Atherosclerosis is a major global health problem. Being a harbinger of a large number of
cardiovascular diseases, it ultimately leads to morbidity and mortality. At the same time …

Netrins belong to the family of laminin-like secreted proteins, which guide axonal migration
and neuronal growth in the developing central nervous system. Over the last 20 years, it has …

Abstract Chemokine receptor 7 (CCR7) is a G protein-coupled receptor containing 7
transmembrane domains that is expressed on various cells, such as naive T/B cells, central …

The immune system performs critical functions to defend against invading pathogens and
maintain tissue homeostasis. Immune cells reside within or are recruited to a host of …