Nanosized nasal emulgel of resveratrol: preparation, optimization, in vitro evaluation and in vivo pharmacokinetic study

HF Salem, RM Kharshoum… - Drug development …, 2019 - Taylor & Francis
Nano-emulgel has become one of the most significant controlled release systems, which
has the advantages of both gels and nano-emulsions. This work aims at the formulation of …

Pharmacokinetic Evaluation of Improved Oral Bioavailability of Valsartan: Proliposomes Versus Self-Nanoemulsifying Drug Delivery System

V Nekkanti, Z Wang, GV Betageri - AAPS PharmSciTech, 2016 - Springer
The objective of this study was to develop proliposomes and self-nanoemulsifying drug
delivery system (SNEDDS) for a poorly bioavailable drug, valsartan, and to compare their in …

Formulation and evaluation of SNEDDS loaded with original lipophenol for the oral route to prevent dry AMD and Stragardt's disease

M Vincent, L Simon, P Brabet, P Legrand, C Dorandeu… - Pharmaceutics, 2022 - mdpi.com
Dry age-related macular degeneration (Dry AMD) and Stargardt's disease (STGD1) are
common eye diseases, characterized by oxidative and carbonyl stress (COS)-inducing …

Coadministration of polypeptide-k and curcumin through solid self-nanoemulsifying drug delivery system for better therapeutic effect against diabetes mellitus …

V Garg, P Kaur, M Gulati, SK Singh… - Assay and drug …, 2019 - liebertpub.com
An attempt has been made to prepare solid self-nanoemulsifying drug delivery system
(SNEDDS) of polypeptide-k (PPK) and curcumin (CRM) using Labrafil M1944 CS as oil …

Formulation of solid self-nanoemulsifying drug delivery systems using N-methyl pyrrolidone as cosolvent

AG Agrawal, A Kumar, PS Gide - Drug development and industrial …, 2015 - Taylor & Francis
Atorvastatin calcium (ATRC) is a poor water soluble drug used for treatment of
hypercholesterolemia. This research is aimed to improve solubility and dissolution rate of …

Self-Generating nano-emulsification techniques for alternatively-routed, bioavailability enhanced delivery, especially for anti-cancers, anti-diabetics, and …

N Akhtar, SAA Mohammed, RA Khan, M Yusuf… - Journal of Drug Delivery …, 2020 - Elsevier
The self-generating nano-emulsifying drug delivery system (SNEDDS) is among the most
effective approaches to enhance the oral bioavailability of a therapeutic agent, especially of …

Spironolactone hyaluronic acid enriched cerosomes (HAECs) for topical management of hirsutism: in silico studies, statistical optimization, ex vivo, and in vivo …

R Albash, AM Fahmy, MIA Hamed, KM Darwish… - Drug …, 2021 - Taylor & Francis
Spironolactone (SP) is a potassium sparing diuretic with antiandrogenic properties. This
study aimed at formulating SP into hyaluronic acid enriched cerosomes (HAECs) for topical …

Response surface optimization of self nano-emulsifying drug delivery system of rosuvastatin calcium for hepatocellular carcinoma

NM Sweed, AM Fayez, SZ El-Emam… - Journal of …, 2021 - Springer
Purpose Rosuvastatin calcium (RSC) is a statin which, in addition to its anti-
hypercholesteremic effects, was found to have a potential anticancer activity. The target of …

Development and characterization of azithromycin-loaded microemulsions: a promising tool for the treatment of bacterial skin infections

A Abruzzo, C Parolin, M Rossi, B Vitali, C Cappadone… - Antibiotics, 2022 - mdpi.com
In recent years, the treatment of bacterial skin infections has been considered a major
healthcare issue due to the growing emergence of antibiotic-resistant strains of …

Capped flexosomes for prominent anti-inflammatory activity: development, optimization, and ex vivo and in vivo assessments

S Ahmed, DE Aziz, MA Sadek, MA Tawfik - Drug Delivery and …, 2024 - Springer
This study aimed to formulate diacerein (DCN)-loaded flexosomes for enhanced efficacy
against osteoarthritis. A 23 D-optimal design was employed, investigating the impact of …