Phenotypic screening has regained momentum in the pharmaceutical industry owing to its
success over target-based screening. Most phenotypic screening relies on nonspecific …

Idiopathic pulmonary fibrosis (IPF) is a severe form of pulmonary fibrosis. IPF is a fatal
disease with no cure and is challenging to diagnose. Unfortunately, due to the elusive …

Background: Cardiac fibroblasts differentiation plays a critical role in cardiac remodeling and
failure, but the underlying molecular mechanisms are still poorly understood. MicroRNAs …

Acute and chronic wounds are common and are a major burden on health care systems.
Chronic wounds with clinical chronicity, high risk of relapse, and complications are attracting …

Heart disease is the leading cause of death in the US and worldwide. In addition to
alterations in cardiomyocyte structure and cellular composition, the adverse ventricular …

Keratoconus (KC) is a progressive degenerative disease that usually occurs bilaterally and
is characterized by corneal thinning and the apical protrusion of the cornea. Oxidative stress …

Musculoskeletal injuries, are growing more and more common in the US1. While there are
many tissue-engineered therapies to combat these injuries, every biomaterial is subject to …

The increasing prevalence of non-communicable diseases, namely cancer, Alzheimer's
(AD) and cardiovascular diseases (CVDs), worldwide continues to be a major health …

Cardiovascular disease (CVD) remains the leading cause of mortality, resulting in 1 out of 4
deaths in the United States at the alarming rate of 1 death every 36 seconds, despite great …