Glucagon like peptide-1 (GLP-1) is an incretin secretory molecule. GLP-1 receptor agonists
(GLP-1RAs) are widely used in the treatment of type 2 diabetes (T2DM) due to their …

Inflammation contributes to many chronic conditions. It is often associated with circulating
pro-inflammatory cytokines and immune cells. GLP-1 levels correlate with disease severity …

A connection between gut microbiota and Parkinson's disease (PD) indicates that dysbiosis
of the gut microbiota might represent a risk factor for PD. Microbiota-targeted interventions …

Alzheimer's disease (AD) is the most common cause of age-related dementia. Increasing
evidence suggests that neuroinflammation mediated by microglia and astrocytes contributes …

The incretin hormone Glucagon-Like Peptide-1 (GLP-1) is best known for its “incretin effect”
in restoring glucose homeostasis in diabetics, however, it is now apparent that it has a …

Alzheimer disease (AD) is the most common form of dementia among the elderly and is
characterized by progressive loss of memory and cognition. Epidemiological data show that …

Prolonged survival of a typical postmitotic neuron hinges on a balance between multiple
processes, among these are a sustenance of ATP production and protection against reactive …

Over the last decade the important concept has emerged that microglia, similar to other
tissue macrophages, assume different phenotypes and serve several effector functions …

Background: Parkinson's disease (PD) is the most common movement disorder affecting up
to 1% of the population above the age of 60 and 4–5% of those above the age of 85. Little …

Mice lacking a microbiota are protected from diet-induced obesity. Previous studies have
shown that feeding a Western diet causes hypothalamic inflammation, which in turn can lead …