Therapeutic advances in non‐small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy

Y Cheng, T Zhang, Q Xu - MedComm, 2021 - Wiley Online Library
Lung cancer still contributes to nearly one‐quarter cancer‐related deaths in the past
decades, despite the rapid development of targeted therapy and immunotherapy in non …

Exploring histopathological and serum biomarkers in lung adenocarcinoma: Clinical applications and translational opportunities

MA Ortega, F Navarro, L Pekarek… - International …, 2022 - spandidos-publications.com
Lung cancer represents one of the most common neoplasms and the main cause of cancer‑
associated death worldwide. Its relationship with different risk factors such as tobacco, which …

Lazertinib versus gefitinib as first-line treatment in patients with EGFR-mutated advanced non–small-cell lung cancer: Results from LASER301

BC Cho, MJ Ahn, JH Kang, RA Soo… - Journal of Clinical …, 2023 - ingentaconnect.com
PURPOSE Lazertinib is a potent, CNS-penetrant, third-generation epidermal growth factor
receptor (EGFR) tyrosine kinase inhibitor. This global, phase III study (LASER301) …

Deep radiotranscriptomics of non-small cell lung carcinoma for assessing molecular and histology subtypes with a data-driven analysis

E Trivizakis, J Souglakos, A Karantanas, K Marias - Diagnostics, 2021 - mdpi.com
Radiogenomic and radiotranscriptomic studies have the potential to pave the way for a
holistic decision support system built on genomics, transcriptomics, radiomics, deep features …

[HTML][HTML] Role of immune checkpoint inhibitor therapy in advanced EGFR-mutant non-small cell lung cancer

N Wiest, U Majeed, K Seegobin, Y Zhao, Y Lou… - Frontiers in …, 2021 - frontiersin.org
Over the last decade, the treatment of advanced non-small cell lung cancer (NSCLC) has
undergone rapid changes with innovations in oncogene-directed therapy and immune …

[HTML][HTML] Molecular biomarker testing for non–small cell lung cancer: consensus statement of the Korean Cardiopulmonary Pathology Study Group

S Chang, HS Shim, TJ Kim, YL Choi… - Journal of Pathology …, 2021 - ncbi.nlm.nih.gov
Molecular biomarker testing is the standard of care for non–small cell lung cancer (NSCLC)
patients. In 2017, the Korean Cardiopulmonary Pathology Study Group and the Korean …

Mutational analysis of EGFR mutations in non-small cell lung carcinoma—an Indian perspective of 212 patients

AK Kaler, K Patel, H Patil, Y Tiwarekar… - International Journal of …, 2022 - mdpi.com
Lung cancer is the world's leading cause of cancer-related deaths. Epidermal growth factor
receptor (EGFR) is one of the critical oncogenes and plays a significant role in tumor …

Network pharmacology and molecular docking study-based approach to explore mechanism of benzimidazole-based anthelmintics for the treatment of lung cancer

A Garg, S Karhana, A Bano, IA Khan… - Journal of …, 2023 - Taylor & Francis
Emerging studies have reported the potential anticancer activity of benzimidazole-based
anthelmintics (BBA) against lung cancer (LC). However, mechanism underlying the …

[HTML][HTML] Nuclear epidermal growth factor receptor as a therapeutic target

B Atwell, P Chalasani, J Schroeder - Exploration of Targeted Anti …, 2023 - ncbi.nlm.nih.gov
Epidermal growth factor receptor (EGFR) is one of the most well-studied oncogenes with
roles in proliferation, growth, metastasis, and therapeutic resistance. This intense study has …

Updated views in targeted therapy in the patient with non-small cell lung cancer

MA Ortega, L Pekarek, F Navarro… - Journal of Personalized …, 2023 - mdpi.com
Non-small cell lung cancer (NSCLC) is the most frequent form of lung cancer and represents
a set of histological entities that have an ominous long-term prognosis, for example …