Biological networks for cancer candidate biomarkers discovery
Due to its extraordinary heterogeneity and complexity, cancer is often proposed as a model
case of a systems biology disease or network disease. There is a critical need of effective …
case of a systems biology disease or network disease. There is a critical need of effective …
Epidermal growth factor receptor tyrosine kinase: A potential target in treatment of non-small-cell lung carcinoma
VV Prabhu, V Prabhu - Journal of Environmental Pathology …, 2017 - dl.begellhouse.com
Lung cancer is responsible for 1.6 million deaths. Approximately 80%− 85% of lung cancers
are of the non-small-cell variety, which includes squamous cell carcinoma, adenocarcinoma …
are of the non-small-cell variety, which includes squamous cell carcinoma, adenocarcinoma …
Tumor-associated macrophages secrete CCL2 and induce the invasive phenotype of human breast epithelial cells through upregulation of ERO1-α and MMP-9
S Lee, E Lee, EY Ko, M Ham, HM Lee, ES Kim, M Koh… - Cancer Letters, 2018 - Elsevier
Tumor-associated macrophages (TAMs) are major components of tumor microenvironment
that promote invasion and metastasis of cancer cells. In this study, we investigated the effect …
that promote invasion and metastasis of cancer cells. In this study, we investigated the effect …
A genome-wide association study of cutaneous squamous cell carcinoma among European descendants
Background: No GWAS on the risk of cutaneous squamous cell carcinoma (SCC) has been
published. We conducted a multistage genome-wide association study (GWAS) to identify …
published. We conducted a multistage genome-wide association study (GWAS) to identify …
PPI-Miner: A Structure and Sequence Motif Co-Driven Protein–Protein Interaction Mining and Modeling Computational Method
Protein–protein interactions (PPIs) play important roles in biological processes of life, and
predicting PPIs becomes a critical scientific issue of concern. Most PPIs occur through small …
predicting PPIs becomes a critical scientific issue of concern. Most PPIs occur through small …
Elucidating protein-protein interactions through computational approaches and designing small molecule inhibitors against them for various diseases
S Sarkar, K Gulati, M Kairamkonda… - Current topics in …, 2018 - ingentaconnect.com
Background: To carry out wide range of cellular functionalities, proteins often associate with
one or more proteins in a phenomenon known as Protein-Protein Interaction (PPI) …
one or more proteins in a phenomenon known as Protein-Protein Interaction (PPI) …
[HTML][HTML] Molecular markers as therapeutic targets in lung cancer
HH Tseng, B He - Chinese journal of cancer, 2013 - ncbi.nlm.nih.gov
Lung cancer is responsible for 29% of cancer deaths in the United States and has very low 5-
year survival rates of approximately 11% in men and 15% in women. Although the early …
year survival rates of approximately 11% in men and 15% in women. Although the early …
Transcriptome profiling analysis of differentially expressed mRNAs and lncRNAs in HepG2 cells treated with peptide 9R-P201
W Liu, R Ding, Y Zhang, C Mao, R Kang, J Meng… - Biotechnology …, 2017 - Springer
Objective To characterize the transcriptome profile of hepatocellular carcinoma (HCC)
HepG2 cells treated with peptide 9R-P201 for further functional verification and HCC drug …
HepG2 cells treated with peptide 9R-P201 for further functional verification and HCC drug …