[HTML][HTML] Antiproliferative, genotoxic activities and quantification of extracts and cucurbitacin B obtained from Luffa operculata (L.) Cogn

NC da Rocha Galucio, D de Araújo Moysés… - Arabian Journal of …, 2022 - Elsevier
The medicinal plant Luffa operculata (L.) Cogn. has therapeutic properties in the treatment of
sinusitis, rhinitis and abortifacient conditions. Ethnopharmacological studies report that the …

[HTML][HTML] Under or absent reporting of light stimuli in testing of anxiety-like behaviors in rodents: the need for standardization

LS Neuwirth, MT Verrengia… - Frontiers in molecular …, 2022 - frontiersin.org
Behavioral neuroscience tests such as the Light/Dark Test, the Open Field Test, the Elevated
Plus Maze Test, and the Three Chamber Social Interaction Test have become both essential …

Investigating the protective effects of Elaeagnus angustifolia fruit extract on hematological parameters and damage of different tissues of male mice exposed to …

MH Sayadi, N Fahoul, J Kharkan, M Khairieh - Nano Select, 2023 - Wiley Online Library
The aim of this study is to investigate the protective effects of Elaeagnus angustifolia fruit
extract (EAFE) on hematology, biochemical parameters, liver enzymes and damage of …

BV2-derived extracellular vesicles modulate microglia inflammatory profile, neuronal plasticity, and behavioural performances in late adult mice

A Rinaldi, M Balietti, E Principi, M De Luca… - Brain, Behavior, and …, 2024 - Elsevier
Background During aging, both the brain and the immune system undergo a progressive
impairment of physiological functions. Microglia, the immunocompetent cells of the central …

Luffa operculata seed proteins: Identification by LC-ESI-MS/MS and biotechnological potential against Candida albicans and C. krusei

AL Silva, LP Bezerra, CDT Freitas, AFB Silva… - Analytical …, 2022 - Elsevier
L operculata is a plant commonly found in the North and Northeast of Brazil. Although the
regional population knows its medicinal potential, there are few scientific studies about its …

[HTML][HTML] The effect of late-life environmental enrichment on stress and anxiety: the role of sex and age-related differences in coping with aversive stimuli

M Balietti, E Principi, L Giacomini, B Giorgetti, F Conti - Heliyon, 2024 - cell.com
Anxiety significantly diminishes the quality of life in older adults, and the drugs used for its
treatment often come with risky side effects. Non-pharmacological protocols could be …

Aged rats with different performances at environmental enrichment onset display different modulation of habituation and aversive memory

M Balietti, A Pugliese, P Fabbietti, M Di Rosa… - Neurobiology of Learning …, 2019 - Elsevier
A wide agreement exists that environmental enrichment (EE) is most beneficial if introduced
early in life, but numerous studies reported that also aged animals remain responsive. As …

In aged rats, differences in spatial learning and memory influence the response to late-life environmental enrichment

M Balietti, A Pugliese, F Conti - Experimental Gerontology, 2021 - Elsevier
It has clearly been demonstrated that cognitive stimulation, physical exercise, and social
engagement help counteract age-related cognitive decline. However, several important …

[HTML][HTML] The gestational exposure to Luffa operculata and a late stressor in young Wistar rats induce sex-specific behavioral, inflammatory, and stress hormone …

IB Suffredini, CS Alves, HV Frias… - Brazilian Journal of …, 2024 - SciELO Brasil
Abstract Luffa operculata (L.) Cogn.(Cucurbitaceae) aqueous extract (EBN) was
gestationally administered to Wistar rats to evaluate sex-related behavioral changes in …

Vertical exposition to Luffa operculata extract deregulates behavior and hypothalamus neurotransmitters in juvenile rats

HV Frias, CS Alves, JC Flório, EF Bondan… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Luffa operculata (L.) Cogn (Cucurbitaceae) is a traditional
plant popularly used in the abortion induction, against sinusitis and is toxic. Aim of the study …