[HTML][HTML] A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection

BK Hulse, H Haberkern, R Franconville… - Elife, 2021 - elifesciences.org
Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …

A neural network for wind-guided compass navigation

TS Okubo, P Patella, I D'Alessandro, RI Wilson - Neuron, 2020 - cell.com
Spatial maps in the brain are most accurate when they are linked to external sensory cues.
Here, we show that the compass in the Drosophila brain is linked to the direction of the wind …

Social behavior and aging: A fly model

DB Brenman‐Suttner, RT Yost… - Genes, Brain and …, 2020 - Wiley Online Library
The field of behavioral genetics has recently begun to explore the effect of age on social
behaviors. Such studies are particularly important, as certain neuropsychiatric disorders with …

Idiosyncratic neural coding and neuromodulation of olfactory individuality in Drosophila

KS Honegger, MAY Smith… - Proceedings of the …, 2020 - National Acad Sciences
Innate behavioral biases and preferences can vary significantly among individuals of the
same genotype. Though individuality is a fundamental property of behavior, it is not currently …

Optogenetic cleavage of the Miro GTPase reveals the direct consequences of real-time loss of function in Drosophila

F Mattedi, E Lloyd-Morris, F Hirth, A Vagnoni - PLoS biology, 2023 - journals.plos.org
Miro GTPases control mitochondrial morphology, calcium homeostasis, and regulate
mitochondrial distribution by mediating their attachment to the kinesin and dynein motor …

The neuroecology of insect-plant interactions: the importance of physiological state and sensory integration

JA Riffell - Current opinion in insect science, 2020 - Elsevier
Highlights•Natural sensory stimuli dynamically change in time.•An insect's sensory system
may reweight the inputs depending on physiological state and the strength of the sensory …

Subtype-specific roles of ellipsoid body ring neurons in sleep regulation in Drosophila

W Yan, H Lin, J Yu, TD Wiggin, L Wu… - Journal of …, 2023 - Soc Neuroscience
The ellipsoid body (EB) is a major structure of the central complex of the Drosophila
melanogaster brain. Twenty-two subtypes of EB ring neurons have been identified based on …

The structure of behavioral variation within a genotype

Z Werkhoven, A Bravin, K Skutt-Kakaria, P Reimers… - Elife, 2021 - elifesciences.org
Individual animals vary in their behaviors. This is true even when they share the same
genotype and were reared in the same environment. Clusters of covarying behaviors …

Examining sleep modulation by Drosophila ellipsoid body neurons

P Singh, A Aleman, JJ Omoto, BC Nguyen… - Eneuro, 2023 - eneuro.org
Recent work in Drosophila has uncovered several neighboring classes of sleep-regulatory
neurons within the central complex. However, the logic of connectivity and network motifs …

Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency

L Granat, DY Knorr, DC Ranson, EL Hamer… - PLoS …, 2023 - journals.plos.org
Mutations in subunits of the mitochondrial NADH dehydrogenase cause mitochondrial
complex I deficiency, a group of severe neurological diseases that can result in death in …