[HTML][HTML] Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …

[HTML][HTML] Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies

N Kumari, SH Choi - Journal of Experimental & Clinical Cancer Research, 2022 - Springer
Cancer immunotherapy has emerged as a novel cancer treatment, although recent
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …

Engineered strategies to enhance tumor penetration of drug-loaded nanoparticles

M Souri, M Soltani, FM Kashkooli… - Journal of Controlled …, 2022 - Elsevier
Nanocarriers have been widely employed in preclinical studies and clinical trials for the
delivery of anticancer drugs. The most important causes of failure in clinical translation of …

Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

[HTML][HTML] Nanoparticles: a new approach to upgrade cancer diagnosis and treatment

Z Yu, L Gao, K Chen, W Zhang, Q Zhang, Q Li… - Nanoscale Research …, 2021 - Springer
Traditional cancer therapeutics have been criticized due to various adverse effects and
insufficient damage to targeted tumors. The breakthrough of nanoparticles provides a novel …

[HTML][HTML] Automatic detection and classification of lung cancer CT scans based on deep learning and ebola optimization search algorithm

TIA Mohamed, ON Oyelade, AE Ezugwu - Plos one, 2023 - journals.plos.org
Recently, research has shown an increased spread of non-communicable diseases such as
cancer. Lung cancer diagnosis and detection has become one of the biggest obstacles in …

[HTML][HTML] Advances and challenges in the treatment of lung cancer

Y Li, B Yan, S He - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Lung cancer accounts for a relatively high proportion of malignant tumors. As the most
prevalent type of lung cancer, non-small cell lung cancer (NSCLC) is characterized by high …

Nanotechnology-based approaches overcome lung cancer drug resistance through diagnosis and treatment

J Li, L Zhu, HF Kwok - Drug Resistance Updates, 2023 - Elsevier
Lung cancer continues to be a malignant tumor with high mortality. Two obstacles interfere
with curative therapy of lung cancer:(i) poor diagnosis at the early stages, as symptoms are …

Versatile role of curcumin and its derivatives in lung cancer therapy

M Ashrafizadeh, M Najafi, P Makvandi… - Journal of cellular …, 2020 - Wiley Online Library
Lung cancer is a main cause of death all over the world with a high incidence rate.
Metastasis into neighboring and distant tissues as well as resistance of cancer cells to …

Inhalable GSH-Triggered Nanoparticles to Treat Commensal Bacterial Infection in In Situ Lung Tumors

Z Ma, H Wang, Z Shi, F Yan, Q Li, J Chen, ZK Cui… - ACS …, 2023 - ACS Publications
Bacterial infection has been considered one of the primary reasons for low survival rate of
lung cancer patients. Herein, we demonstrated that a kind of mesoporous silica …