[HTML][HTML] New approaches to dendritic cell-based therapeutic vaccines against HIV-1 infection
M Espinar-Buitrago, MA Muñoz-Fernández - Frontiers in immunology, 2022 - frontiersin.org
Due to the success of combined antiretroviral therapy (cART) in recent years, the
pathological outcome of Human Immunodeficiency Virus type 1 (HIV-1) infection has …
pathological outcome of Human Immunodeficiency Virus type 1 (HIV-1) infection has …
Antiretroviral treatment interruption among people living with HIV during COVID‐19 outbreak in China: a nationwide cross‐sectional study
Y Sun, H Li, G Luo, X Meng, W Guo… - Journal of the …, 2020 - Wiley Online Library
Introduction Social disruption associated with coronavirus disease 2019 (COVID‐19)
threatens to impede access to regular healthcare, including for people living with HIV …
threatens to impede access to regular healthcare, including for people living with HIV …
[HTML][HTML] Analytical treatment interruption in HIV trials: statistical and study design considerations
L Zheng, C Tierney, RJ Bosch - Current HIV/AIDS Reports, 2021 - Springer
Abstract Purpose of Review Analytical treatment interruption (ATI) remains an essential
component in clinical studies investigating novel agents or combination treatment strategies …
component in clinical studies investigating novel agents or combination treatment strategies …
Definition of Virological Endpoints Improving the Design of Human Immunodeficiency Virus (HIV) Cure Strategies Using Analytical Antiretroviral Treatment Interruption
M Alexandre, M Prague, E Lhomme… - Clinical Infectious …, 2024 - academic.oup.com
Background Analytical treatment interruption (ATI) is the gold standard in HIV research for
assessing the capability of new therapeutic strategies to control viremia without antiretroviral …
assessing the capability of new therapeutic strategies to control viremia without antiretroviral …
[HTML][HTML] Perceptions of HIV cure and willingness to participate in HIV cure-related trials among people enrolled in the Netherlands cohort study on acute HIV infection
P van Paassen, M Dijkstra, HL Peay, C Rokx… - Journal of virus …, 2022 - Elsevier
Background People who initiate antiretroviral therapy (ART) during acute HIV infection are
potential candidates for HIV cure-related clinical trials, as early ART reduces the size of the …
potential candidates for HIV cure-related clinical trials, as early ART reduces the size of the …
HIV-1 therapeutic vaccines in clinical development to intensify or replace antiretroviral therapy: the promising results of the Tat vaccine
A Cafaro, B Ensoli - Expert Review of Vaccines, 2022 - Taylor & Francis
Introduction Upon the introduction of the combination antiretroviral therapy (cART), HIV
infection has become a chronic disease. However, cART is unable to eradicate the virus and …
infection has become a chronic disease. However, cART is unable to eradicate the virus and …
The Essential Need for Trust When Transmission Risk Cannot Be Eliminated in HIV‐Remission Trials
S Rennie, G Henderson, N Phanuphak… - Ethics & Human …, 2023 - Wiley Online Library
Analytic treatment interruption (ATI) is scientifically necessary in HIV‐remission (“cure”)
studies to test the effects of new interventions. However, stopping antiretroviral treatment …
studies to test the effects of new interventions. However, stopping antiretroviral treatment …
[HTML][HTML] Persistent HIV-1 transcription in CD4+ T cells from ART-suppressed individuals can originate from biologically competent proviruses
M Vignoles, V Andrade, M Noguera, C Brander… - Journal of Virus …, 2021 - Elsevier
HIV-1 is able to persist in the face of potent antiretroviral therapy (ART). A number of
strategies are being explored to allow ART-free viral remission or viral eradication. In order …
strategies are being explored to allow ART-free viral remission or viral eradication. In order …
Definition of viroIogical endpoints improving the design of HIV cure strategies using analytical antiretroviral treatment interruption
Background. Analytical treatment interruption (ATI) is the gold standard in HIV research to
validate the ability of novel therapeutic strategies to long-term control viremia without …
validate the ability of novel therapeutic strategies to long-term control viremia without …
[HTML][HTML] Immune-Related Gene Profile in HIV-Infected Patients with Discordant Immune Response
Y Hamidi, E Aliasgari, P Basimi… - Iranian biomedical …, 2022 - ncbi.nlm.nih.gov
Background: In spite of many reports on persistent low CD4 T cell counts and change in
immune-related gene expression level in patients with HIV infection, there is still uncertainty …
immune-related gene expression level in patients with HIV infection, there is still uncertainty …