[HTML][HTML] New genetic and epigenetic insights into the chemokine system: The latest discoveries aiding progression toward precision medicine
H Xu, S Lin, Z Zhou, D Li, X Zhang, M Yu… - Cellular & Molecular …, 2023 - nature.com
Over the past thirty years, the importance of chemokines and their seven-transmembrane G
protein-coupled receptors (GPCRs) has been increasingly recognized. Chemokine …
protein-coupled receptors (GPCRs) has been increasingly recognized. Chemokine …
[HTML][HTML] Emerging role of different DNA methyltransferases in the pathogenesis of cancer
P Liu, F Yang, L Zhang, Y Hu, B Chen… - Frontiers in …, 2022 - frontiersin.org
DNA methylation is one of the most essential epigenetic mechanisms to regulate gene
expression. DNA methyltransferases (DNMTs) play a vital role in DNA methylation in the …
expression. DNA methyltransferases (DNMTs) play a vital role in DNA methylation in the …
Mechanisms of DNA methylation and histone modifications
The field of genetics has expanded a lot in the past few decades due to the accessibility of
human genome sequences, but still, the regulation of transcription cannot be explicated …
human genome sequences, but still, the regulation of transcription cannot be explicated …
Sex-specific DNA methylation in saliva from the multi-ethnic Future of Families and Child Wellbeing Study
A Reiner, KM Bakulski, JD Fisher, JF Dou… - Epigenetics, 2023 - Taylor & Francis
The prevalence and severity of many diseases differs by sex, potentially due to sex-specific
patterns in DNA methylation. Autosomal sex-specific differences in DNA methylation have …
patterns in DNA methylation. Autosomal sex-specific differences in DNA methylation have …
[HTML][HTML] DNA Hypomethylation Is Associated with Increased Inflammation in Peripheral Blood Neutrophils of Children with Autism Spectrum Disorder: Understanding …
Autism spectrum disorder (ASD) is a multidimensional disorder in which environmental,
immune, and genetic factors act in concert to play a crucial role. ASD is characterized by …
immune, and genetic factors act in concert to play a crucial role. ASD is characterized by …
[HTML][HTML] The emerging role of epigenetics in metabolism and endocrinology
BZ Sibuh, S Quazi, H Panday, R Parashar, NK Jha… - Biology, 2023 - mdpi.com
Simple Summary Epigenetics is a somatic, heritable pattern of gene expression or cellular
phenotype mediated by structural changes in chromatin that occur without altering the DNA …
phenotype mediated by structural changes in chromatin that occur without altering the DNA …
DNA methylation in autoimmune thyroid disease
N Lafontaine, SG Wilson… - The Journal of Clinical …, 2023 - academic.oup.com
Graves disease and Hashimoto disease form part of the spectrum of autoimmune thyroid
disease (AITD), to which genetic and environmental factors are recognized contributors …
disease (AITD), to which genetic and environmental factors are recognized contributors …
DNA methylation and transcriptome signatures of the PDCD1 gene in ankylosing spondylitis
Y Wu, Y Chen, X Sun, Y Deng, M Ni, F Pan - Genes & Immunity, 2023 - nature.com
Ankylosing spondylitis (AS) is an autoimmune-related inflammatory arthritis. The association
between the DNA methylation and mRNA expression of PDCD1 gene with the susceptibility …
between the DNA methylation and mRNA expression of PDCD1 gene with the susceptibility …
[HTML][HTML] Genetic and epigenetic regulation of MEFV gene and their impact on clinical outcome in auto-inflammatory familial mediterranean fever patients
ME Zekry, AAM Sallam, SG AbdelHamid… - Current Issues in …, 2023 - mdpi.com
Epigenetic modifications play a pivotal role in autoimmune/inflammatory disorders and could
establish a bridge between personalized medicine and disease epidemiological contexts …
establish a bridge between personalized medicine and disease epidemiological contexts …
[HTML][HTML] The emerging role of TET enzymes in the immune microenvironment at the maternal-fetal interface during decidualization and early pregnancy
M Jin, J Ji, X Chen, Y Zhou, D Wang, A Liu - Frontiers in Immunology, 2023 - frontiersin.org
A dysregulated immune microenvironment at the maternal-fetal interface in early pregnancy
may lead to early pregnancy loss, fetal growth restriction, and preeclampsia. However, major …
may lead to early pregnancy loss, fetal growth restriction, and preeclampsia. However, major …