Over the past thirty years, the importance of chemokines and their seven-transmembrane G
protein-coupled receptors (GPCRs) has been increasingly recognized. Chemokine …

DNA methylation is one of the most essential epigenetic mechanisms to regulate gene
expression. DNA methyltransferases (DNMTs) play a vital role in DNA methylation in the …

The field of genetics has expanded a lot in the past few decades due to the accessibility of
human genome sequences, but still, the regulation of transcription cannot be explicated …

The prevalence and severity of many diseases differs by sex, potentially due to sex-specific
patterns in DNA methylation. Autosomal sex-specific differences in DNA methylation have …

Autism spectrum disorder (ASD) is a multidimensional disorder in which environmental,
immune, and genetic factors act in concert to play a crucial role. ASD is characterized by …

Simple Summary Epigenetics is a somatic, heritable pattern of gene expression or cellular
phenotype mediated by structural changes in chromatin that occur without altering the DNA …

Graves disease and Hashimoto disease form part of the spectrum of autoimmune thyroid
disease (AITD), to which genetic and environmental factors are recognized contributors …

Ankylosing spondylitis (AS) is an autoimmune-related inflammatory arthritis. The association
between the DNA methylation and mRNA expression of PDCD1 gene with the susceptibility …

Epigenetic modifications play a pivotal role in autoimmune/inflammatory disorders and could
establish a bridge between personalized medicine and disease epidemiological contexts …

A dysregulated immune microenvironment at the maternal-fetal interface in early pregnancy
may lead to early pregnancy loss, fetal growth restriction, and preeclampsia. However, major …