[HTML][HTML] Thyroid hormone receptor beta as tumor suppressor: untapped potential in treatment and diagnostics in solid tumors
CD Davidson, NE Gillis, FE Carr - Cancers, 2021 - mdpi.com
Simple Summary Dysregulation of the thyroid hormone receptor beta (TRβ) is characteristic
of many solid and endocrine-related tumors. Despite a recognized role as a tumor …
of many solid and endocrine-related tumors. Despite a recognized role as a tumor …
[HTML][HTML] Unraveling the role of the mitochondrial one-carbon pathway in undifferentiated thyroid cancer by multi-omics analyses
SE Lee, S Park, S Yi, NR Choi, MA Lim… - Nature …, 2024 - nature.com
The role of the serine/glycine metabolic pathway (SGP) has recently been demonstrated in
tumors; however, the pathological relevance of the SGP in thyroid cancer remains …
tumors; however, the pathological relevance of the SGP in thyroid cancer remains …
Inhibition of glycogen metabolism induces reactive oxygen species-dependent cytotoxicity in anaplastic thyroid cancer in female mice
CD Davidson, JA Tomczak, E Amiel, FE Carr - Endocrinology, 2022 - academic.oup.com
Anaplastic thyroid cancer (ATC) is one of the most lethal solid tumors, yet there are no
effective, long-lasting treatments for ATC patients. Most tumors, including tumors of the …
effective, long-lasting treatments for ATC patients. Most tumors, including tumors of the …
[HTML][HTML] Glutor, a glucose transporter inhibitor, exerts antineoplastic action on tumor cells of thymic origin: Implication of modulated metabolism, survival, oxidative …
Neoplastic cells overexpress glucose transporters (GLUT), particularly GLUT1 and GLUT3,
to support altered metabolism. Hence, novel strategies are being explored to effectively …
to support altered metabolism. Hence, novel strategies are being explored to effectively …
[HTML][HTML] Diagnostics of Thyroid Cancer Using Machine Learning and Metabolomics
The objective of this research is, with the analysis of existing data of thyroid cancer (TC)
metabolites, to develop a machine-learning model that can diagnose TC using metabolite …
metabolites, to develop a machine-learning model that can diagnose TC using metabolite …
[PDF][PDF] Mitochondrial SHMT2 is a crucial therapeutic target in dedifferentiated thyroid cancer
SE Lee, S Park, S Yi, MA Lim, JW Chang, HR Won… - 2022 - scholar.archive.org
The roles of the serine/glycine metabolic pathway (SGP) have recently been evident in
certain types of tumor physiology; however, the pathological relevance of SGP in …
certain types of tumor physiology; however, the pathological relevance of SGP in …
Enhancing Thyroid Cancer Diagnostics Through Hybrid Machine Learning and Metabolomics Approaches.
MG Raj - … Journal of Advanced Computer Science & …, 2024 - search.ebscohost.com
Thyroid cancer, a prevalent endocrine malignancy, necessitates advanced diagnostic
techniques for accurate and early detection. This study introduces an innovative approach …
techniques for accurate and early detection. This study introduces an innovative approach …
Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of cancer-associated death in the West. This type of cancer has a very poor prognosis notably …
G Yang, Y Hori, A Couvineau - … mitochondrial dynamics and …, 2023 - books.google.com
Pancreatic cancers widely represented (> 90%) by pancreatic ductal adenocarcinoma
(PDAC) are the most lethal human digestive cancer with a very poor 5-year-survival rate …
(PDAC) are the most lethal human digestive cancer with a very poor 5-year-survival rate …
Inhibition of Glycogen Metabolism Induces Reactive Oxygen Species-Dependent Apoptosis in Anaplastic Thyroid Cancer
CD Davidson, JA Tomczak, E Amiel, FE Carr - bioRxiv, 2022 - biorxiv.org
Anaplastic thyroid cancer (ATC) is one of the most lethal solid tumors, yet there are no
effective, long-lasting treatments for ATC patients. Most tumors, including tumors of the …
effective, long-lasting treatments for ATC patients. Most tumors, including tumors of the …