Relationship between fluoroquinolone structure and neurotoxicity revealed by zebrafish neurobehavior
C Xiao, Y Han, Y Liu, J Zhang, C Hu - Chemical Research in …, 2018 - ACS Publications
Central nervous system side effects are one of the most frequently reported adverse
reactions of fluoroquinolones (FQs). However, the mechanism is not fully understood. In this …
reactions of fluoroquinolones (FQs). However, the mechanism is not fully understood. In this …
Understanding drug-induced movement disorders: causes, symptoms, and treatment
ER Santos - 2024 - preprints.org
Drug-induced movement disorders (DIMDs) are a group of neurological conditions caused
by the use of certain medications. These disorders can significantly impact a person's quality …
by the use of certain medications. These disorders can significantly impact a person's quality …
Fluoroquinolones: old drugs, putative new toxicities
C Bove, RA Baldock, O Champigneulle… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Fluoroquinolone (FQ) antibiotics were approved in 1986 for treatment of urinary
tract infections, sinusitis, and bronchitis. Numerous putative FQ-associated adverse events …
tract infections, sinusitis, and bronchitis. Numerous putative FQ-associated adverse events …
Gut microbiota and serum metabolomic alterations in modulating the impact of fecal microbiota transplantation on ciprofloxacin-induced seizure susceptibility
S Zou, Y Li, Q Zou, M Yang, H Li, R Niu, H Lai… - Frontiers in …, 2024 - frontiersin.org
Introduction The gut microbiota and the microbiota-gut-brain axis have gained considerable
attention in recent years, emerging as key players in the mechanisms that mediate the …
attention in recent years, emerging as key players in the mechanisms that mediate the …
Quinolone antibiotics and suicidal behavior: analysis of the World Health Organization's adverse drug reactions database and discussion of potential mechanisms
J Samyde, P Petit, D Hillaire-Buys, JL Faillie - Psychopharmacology, 2016 - Springer
Rationale Several case-reports suggest that the use of quinolones may increase the risk of
psychiatric adverse reactions such as suicidal behaviors. Objectives The aim of this study is …
psychiatric adverse reactions such as suicidal behaviors. Objectives The aim of this study is …
Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues
Fluoroquinolones (FQs) are synthetic and broad-spectrum antimicrobial drugs derived from
nalidixic acid. FQs are used against SARS-CoV-2 in our country, and for the treatment of …
nalidixic acid. FQs are used against SARS-CoV-2 in our country, and for the treatment of …
Augmentation of 5-aminolevulinic acid treatment of glioblastoma by adding ciprofloxacin, deferiprone, 5-fluorouracil and febuxostat: the CAALA regimen
The CAALA (Complex Augmentation of ALA) regimen was developed with the goal of
redressing some of the weaknesses of 5-aminolevulinic acid (5-ALA) use in glioblastoma …
redressing some of the weaknesses of 5-aminolevulinic acid (5-ALA) use in glioblastoma …
Combination therapy with ciprofloxacin and third-generation cephalosporin versus third-generation cephalosporin monotherapy in Escherichia coli meningitis in …
M Tauzin, N Ouldali, C Lévy, S Béchet, R Cohen… - Clinical Microbiology …, 2019 - Elsevier
Objectives Escherichia coli is the second cause of bacterial meningitis in neonates. Despite
the use for 35 years of third-generation cephalosporins (3GCs), high morbidity and mortality …
the use for 35 years of third-generation cephalosporins (3GCs), high morbidity and mortality …
Cerebral effect of optimized Allium sativum oil-loaded chitosan nanorods: GC-MS analysis and in vitro/in vivo evaluation
R Kamel, A Salama, NM Shaffie, NM Salah - Food & function, 2020 - pubs.rsc.org
The chemical constituents of Allium sativum (garlic) oil were investigated using the GC/MS
technique after silylation, and the presence of several fatty acids and their esters was …
technique after silylation, and the presence of several fatty acids and their esters was …
Fumaric acid protects rats from ciprofloxacin-provoked depression through modulating TLR4, Nrf-2, and p190-rho GTP
MM Khalaf, HM Mahmoud, MA Kandeil… - Drug and Chemical …, 2024 - Taylor & Francis
Depression is a persistent illness affecting health, behavior, and performance in life.
Worldwide morbidity and mortality are caused by depression. The current study intended to …
Worldwide morbidity and mortality are caused by depression. The current study intended to …