Impact of the host response and osteoblast lineage cells on periodontal disease
M Zhou, DT Graves - Frontiers in immunology, 2022 - frontiersin.org
Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …
RNA-seq experiments have provided new insight into how resident cells and infiltrating …
[HTML][HTML] Pharmaceutical treatment of bone loss: From animal models and drug development to future treatment strategies
MB Brent - Pharmacology & Therapeutics, 2023 - Elsevier
Animal models are fundamental to advance our knowledge of the underlying
pathophysiology of bone loss and to study pharmaceutical countermeasures against it. The …
pathophysiology of bone loss and to study pharmaceutical countermeasures against it. The …
[HTML][HTML] Abaloparatide: a review of preclinical and clinical studies
MB Brent - European Journal of Pharmacology, 2021 - Elsevier
Osteoporosis is a debilitating disease characterized by reduced bone mineral density and
an increased risk of fractures. This review aims to provide a comprehensive overview of, and …
an increased risk of fractures. This review aims to provide a comprehensive overview of, and …
Muscle-derived extracellular vesicles improve disuse-induced osteoporosis by rebalancing bone formation and bone resorption
H Huang, S Ma, X Xing, X Su, X Xu, Q Tang, X Gao… - Acta biomaterialia, 2023 - Elsevier
Osteoporosis is a highly prevalent skeletal bone disorder worldwide with characteristics of
reduced bone mass and increased risk of osteoporotic fractures. It has been predicted to …
reduced bone mass and increased risk of osteoporotic fractures. It has been predicted to …
Adverse effect of botulinum toxin‐A injections on mandibular bone: A systematic review and meta‐analysis
MS Moussa, D Bachour… - Journal of oral …, 2024 - Wiley Online Library
Abstract Introduction Botulinum toxin‐A (BTX) is a potent neurotoxin that is emerging in the
scope of dental practice for its ability to temporarily paralyse musculature and reduce …
scope of dental practice for its ability to temporarily paralyse musculature and reduce …
[HTML][HTML] A review of the skeletal effects of exposure to high altitude and potential mechanisms for hypobaric hypoxia-induced bone loss
MB Brent - Bone, 2022 - Elsevier
Mountaineering and exposure to high altitude result in physiological adaptations to the
reduced inspiratory oxygen availability. Acute mountain sickness (AMS), high altitude …
reduced inspiratory oxygen availability. Acute mountain sickness (AMS), high altitude …
Pulsed electro-magnetic field (pemf) effect on bone healing in animal models: a review of its efficacy related to different type of damage
M Di Bartolomeo, F Cavani, A Pellacani, A Grande… - Biology, 2022 - mdpi.com
Simple Summary Pulsed electromagnetic fields (PEMFs) are a type of biophysical
stimulation that has been shown to be effective in improving bone regeneration and …
stimulation that has been shown to be effective in improving bone regeneration and …
Impact of botulinum toxin injection into the masticatory muscles on mandibular bone: A systematic review
M Owen, B Gray, N Hack, L Perez… - Journal of oral …, 2022 - Wiley Online Library
Background Botulinum toxin type A (BoNTA) injection into the masticatory muscles has been
widely used to treat a number of painful and nonpainful conditions; however, no systematic …
widely used to treat a number of painful and nonpainful conditions; however, no systematic …
[HTML][HTML] Anti-sclerostin antibodies and abaloparatide have additive effects when used as a countermeasure against disuse osteopenia in female rats
Prolonged disuse and substantial mechanical unloading are particularly damaging to
skeletal integrity. Preclinical studies in rodents and clinical studies have highlighted the …
skeletal integrity. Preclinical studies in rodents and clinical studies have highlighted the …
Progression of microstructural deterioration in load-bearing immobilization osteopenia
H Koseki, M Osaki, Y Honda, S Sunagawa, C Imai… - PLoS …, 2022 - journals.plos.org
Purpose Immobilization osteopenia is a major healthcare problem in clinical and social
medicine. However, the mechanisms underlying this bone pathology caused by …
medicine. However, the mechanisms underlying this bone pathology caused by …