SMARCA4 vulnerability in H3K27M midline glioma: A silver bullet for a lethal disease Page 1
Spotlight SMARCA4 vulnerability in H3K27M midline glioma: A silver bullet for a lethal disease …

Transplantation of Neural Stem/Progenitor Cells (NPCs) is a promising regenerative strategy
to promote neural repair following injury and degeneration because of the ability of these …

Deregulation of the epigenome underlies oncogenesis in numerous primary brain tumours
in children and young adults. In this review, we describe how recurrent mutations in …

Despite improvements in cancer patient outcomes seen in the past decade, tumor resistance
to therapy remains a major impediment to achieving durable clinical responses. Intratumoral …

Introduction: Pediatric brain tumours (PBT) are one of the most common malignancies
during childhood, with variable severity according to the location and histological type …

Bioenergetics describe the biochemical processes responsible for energy supply in
organisms. When these changes become dysregulated in brain development, multiple …

Importance The ability to predict the efficacy of systemic psoriasis therapy based on immune
profiles in skin biopsies could reduce the use of inappropriate treatment and its associated …

Pediatric cancers represent a tragic but also promising area for gene therapy. Although
conventional treatments have improved survival rates, there is still a need for targeted and …

Rhabdoid tumors (RT) are rare and highly aggressive pediatric neoplasms. Their
epigenetically-driven intertumoral heterogeneity is well described; however, the cellular …

Exercise is recommended for the healthy population as it increases fitness and prevents
diseases. Moreover, exercise is also applied as an adjunct therapy for patients with various …